von Wagner, Christian, Ghanouni, Alex, Halligan, Steve, Smith, Samuel, Dadswell, Edward, Lilford, Richard, Morton, Dion, Atkin, Wendy and Wardle, Jane (2012) Patient acceptability and psychologic consequences of CT colonography compared with those of colonoscopy : results from a multicenter randomized controlled trial of symptomatic patients. Radiology, 263 (3). pp. 723-731. doi:10.1148/radiol.12111523

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Abstract

Symptoms suggestive of colorectal cancer are nonspecific and common in the general population; only 5% of patients investigated have colorectal cancer (1). Diagnosis should be safe and acceptable because most of those tested have no abnormalities detected. Colonoscopy is widely regarded as the reference standard test for colorectal neoplasia, combining accuracy with efficiency because diagnosis and polypectomy can be combined. Colonoscopy, however, can be uncomfortable, requires analgesia and/or sedation, and carries some risks (2), particularly in older patients. Computed tomographic (CT) colonography is possibly more acceptable to patients (3,4) and relatively safe (5), while maintaining sensitivity for cancer. A recent meta-analysis showed a mean sensitivity of 96% for CT colonography versus 95% for colonoscopy (6).

Item Type:	Journal Article
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) Faculty of Medicine > Warwick Medical School
Journal or Publication Title:	Radiology
Publisher:	Radiological Society of North America, Inc.
ISSN:	0033-8419
Official Date:	2012
Dates:	Date Event 2012 UNSPECIFIED
Volume:	263
Number:	3
Page Range:	pp. 723-731
DOI:	10.1148/radiol.12111523
Status:	Peer Reviewed
Publication Status:	Published

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