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Cardiovascular risk factors among people being treated for HIV in Nepal : a cross-sectional study
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Aryal, Nirmal, Marais, Debbi and Simkhada, Padam (2014) Cardiovascular risk factors among people being treated for HIV in Nepal : a cross-sectional study. Journal of Clinical Research in HIV AIDS and Prevention, 1 (4). pp. 22-36. doi:doi:10.14302/issn.2324-7339.jcrhap-12-157 ISSN 2324-7339.
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Official URL: http://dx.doi.org/10.14302/issn.2324-7339.jcrhap-1...
Abstract
Background: Human Immunodeficiency Virus (HIV) and antiretroviral therapy (ART) are found to be strongly associated with cardiovascular diseases. Data are sparse on the prevalence and distribution of cardiovascular risk factors among people being treated for HIV in South Asia region.
Methods: A cross-sectional study of 103 HIV patients (51 women and 52 men) attending routine follow-up consultations at the largest ART centre in Nepal was conducted. Data on several cardiovascular risk factors were collected through interview questionnaires, biophysical measurements and consulting medical records.
Results: The most common cardiovascular risk factors observed were central obesity [34.6%, 95% Confidence Interval (CI): 25.3% to 43.9%], chronic kidney disease [20.7% (95% CI: 11.6% to 29.7%)] and tachycardia [20.6% (95% CI: 12.7% to 28.5%)]. Females were significantly more likely to have central obesity (male 9.8% vs. female 60%, p=0.016) and chronic kidney disease (male 15.4% vs. female 26.3%, p=0.003) as compared to the males. Participants were fairly active but a large proportion, especially men, had smoked [65% (95% CI: 57%-72.3%)], used tobacco products [66% (95% CI: 56.4%-74.4%)] or drugs (53.8% of the men) and consumed alcohol [60.2% (95% CI: 50.5%-69.1%)].
Conclusion: A high prevalence of several cardiovascular risk factors was observed among patients being treated for HIV in Nepal. Further larger studies are warranted to better understand the relevance and public health impact of cardiovascular risk factors in this region.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > ( - July 2016) Health Education Hub Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Journal of Clinical Research in HIV AIDS and Prevention | ||||||
| ISSN: | 2324-7339 | ||||||
| Official Date: | 10 February 2014 | ||||||
| Dates: |
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| Volume: | 1 | ||||||
| Number: | 4 | ||||||
| Page Range: | pp. 22-36 | ||||||
| DOI: | doi:10.14302/issn.2324-7339.jcrhap-12-157 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Open Access (Creative Commons) |
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