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Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD)
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Arasaradnam, Ramesh P., McFarlane, Michael J., Daulton, Emma, Skinner, Jim, O’Connell, Nicola, Wurie, Subiatu, Chambers, Samantha, Nwokolo, Chuka U., Bardhan, Karna Dev, Savage, Richard S. and Covington, James A. (2016) Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD). Digestive and Liver Disease, 48 (2). pp. 148-153. pii/S1590865815301067. doi:10.1016/j.dld.2015.10.013
An open access version can be found in:
Official URL: http://dx.doi.org/10.1016/j.dld.2015.10.013
Abstract
Early inflammatory bowel disease (IBD) diagnosis remains a clinical challenge. Volatile organic compounds (VOCs) have shown distinct patterns in Crohn's disease (CD) and ulcerative colitis (UC). VOC production, reflecting gut fermentome metabolites, is perturbed in IBD. VOC sampling is non-invasive, with various compounds identified from faecal, breath and urine samples. This study aimed to determine if FAIMS (field asymmetric ion mobility spectroscopy) analysis of exhaled VOCs could distinguish IBD from controls.
| Item Type: | Journal Article | ||||||||||
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| Divisions: | Faculty of Science > Centre for Complexity Science Faculty of Science > Engineering Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
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| Journal or Publication Title: | Digestive and Liver Disease | ||||||||||
| Publisher: | W. B. Saunders Co. Ltd. | ||||||||||
| ISSN: | 1590-8658 | ||||||||||
| Official Date: | 2 November 2016 | ||||||||||
| Dates: |
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| Volume: | 48 | ||||||||||
| Number: | 2 | ||||||||||
| Page Range: | pp. 148-153 | ||||||||||
| Article Number: | pii/S1590865815301067 | ||||||||||
| DOI: | 10.1016/j.dld.2015.10.013 | ||||||||||
| Status: | Peer Reviewed | ||||||||||
| Publication Status: | Published | ||||||||||
| Access rights to Published version: | Open Access | ||||||||||
| Open Access Version: |
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