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Facial structure in the sudden infant death syndrome : case-control study
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Rees, Karen, Wright, A., Keeling, J. W and Douglas, N. J (1998) Facial structure in the sudden infant death syndrome : case-control study. BMJ, 317 (7152). pp. 179-180. doi:10.1136/bmj.317.7152.179 ISSN 0959-8138.
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Official URL: http://dx.doi.org/10.1136/bmj.317.7152.179
Abstract
The cause of the sudden infant death syndrome is unclear. Polygraphic recordings of 30 infants who subsequently died of the syndrome showed a significant increase in mixed and obstructive apnoeas compared with well matched controls. Postmortem examination suggests upper airway narrowing in victims of the syndrome. The decreased number of cases of sudden infant death syndrome after advice to put infants to sleep supine suggests a posture dependent cause, and recent evidence suggests that upper airways of sleeping infants are more widely patent supine than prone. Thus sleeping supine might decrease obstructive apnoeas.
An increased frequency of sudden infant death syndrome and apparent life threatening events in infants has been found in the families of patients with the obstructive sleep apnoea/hypopnoea syndrome. We found that retroposition of the maxilla was a common feature in families who had both the obstructive sleep apnoea/hypopnoea and sudden infant death syndromes.3 We also found that obstructive apnoeas in adult family members of patients with the obstructive sleep apnoea/hypopnoea syndrome were related to retroposition of the maxilla and mandible.5
We therefore tested the hypothesis that victims of the sudden infant death syndrome have backset maxillae and mandibles, which would predispose them to narrowing and occlusion of their upper airways.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Statistics and Epidemiology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | BMJ | ||||
ISSN: | 0959-8138 | ||||
Official Date: | 18 July 1998 | ||||
Dates: |
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Volume: | 317 | ||||
Number: | 7152 | ||||
Page Range: | pp. 179-180 | ||||
DOI: | 10.1136/bmj.317.7152.179 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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