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Cytokinesis and cancer
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Sagona, Antonia P. and Stenmark, Harald (2010) Cytokinesis and cancer. FEBS Letters, 584 (12). pp. 2652-2661. doi:10.1016/j.febslet.2010.08.016 ISSN 0014-5793.
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Official URL: http://dx.doi.org/10.1016/j.febslet.2010.03.044
Abstract
Cytokinesis is the final stage of cell division during which the two daughter cells separate completely. Although less well understood than some of the earlier phases of the cell cycle, recent discoveries have shed light on the mechanisms that orchestrate this process, including cleavage furrow formation, midbody maturation and abscission. One of the reasons why research on cytokinesis has been attracting increasing attention is the concept that failure of this process in mammals is associated with carcinogenesis. In this minireview, we will discuss the possible links between cytokinesis and cancer, and highlight key mechanisms that connect these processes.
Item Type: | Journal Article | ||||||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||||
Journal or Publication Title: | FEBS Letters | ||||||||||
Publisher: | Elsevier BV | ||||||||||
ISSN: | 0014-5793 | ||||||||||
Official Date: | 18 June 2010 | ||||||||||
Dates: |
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Volume: | 584 | ||||||||||
Number: | 12 | ||||||||||
Page Range: | pp. 2652-2661 | ||||||||||
DOI: | 10.1016/j.febslet.2010.08.016 | ||||||||||
Status: | Peer Reviewed | ||||||||||
Publication Status: | Published |
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