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Bacterial cell division : experimental and theoretical approaches to the divisome

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Broughton, Claire E., Roper, David I., Berg, Hugo van den and Rodger, Alison (2015) Bacterial cell division : experimental and theoretical approaches to the divisome. Science Progress, 98 (4). pp. 313-345. doi:10.3184/003685015X14461391862881

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Official URL: http://dx.doi.org/10.3184/003685015X14461391862881

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Abstract

Cell division is a key event in the bacterial life cycle. It involves constriction at the midcell, so that one cell can give rise to two daughter cells. This constriction is mediated by a ring composed of fibrous multimers of the protein FtsZ. However, a host of additional factors is involved in the formation and dynamics of this “Z-ring” and this complicated apparatus is collectively known as the “divisome”. We review the literature, with an emphasis on mathematical modelling, and show how such theoretical efforts have helped experimentalists to make sense of the at times bewildering data, and plan further experiments.

Item Type: Journal Article
Divisions: Faculty of Science > Life Sciences (2010- )
Journal or Publication Title: Science Progress
Publisher: Science Reviews 2000 Ltd.
ISSN: 0036-8504
Official Date: 1 December 2015
Dates:
DateEvent
1 December 2015Published
Volume: 98
Number: 4
Page Range: pp. 313-345
DOI: 10.3184/003685015X14461391862881
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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