The Library
The salicylic acid dependent and independent effects of NMD in plants
Tools
Tools
Tools
Rayson, Samantha, Ashworth, Mary, Torres Zabala, Marta de, Grant, Murray and Davies, Brendan (2012) The salicylic acid dependent and independent effects of NMD in plants. Plant Signaling & Behavior, 7 (11). pp. 1434-1437. doi:10.4161/psb.21960
|
PDF
WRAP_Grant_The salicylic acid dependent and independent effects of NMD in plants.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial. Download (1662Kb) | Preview |
Official URL: http://dx.doi.org/10.4161/psb.21960
Abstract
In eukaryotes, nonsense-mediated mRNA decay (NMD) targets aberrant and selected non-aberrant mRNAs for destruction. A recent screen for mRNAs showing increased abundance in Arabidopsis NMD-deficient mutants revealed that most are associated with the salicylic acid (SA)-mediated defense pathway. mRNAs with conserved peptide upstream open reading frames (CpuORFs or CuORFs) are hugely overrepresented among the smaller class of NMD-regulated transcripts not associated with SA. Here we show that the common phenotypes observed in Arabidopsis NMD mutants are SA-dependent, whereas the upregulation of CpuORF-containing transcripts in NMD mutants is independent of SA. We speculate that CpuORFs could allow the conditional targeting of mRNAs for destruction using the NMD pathway.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | S Agriculture > SB Plant culture | ||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||
| Library of Congress Subject Headings (LCSH): | Salicylic acid, Arabidopsis, Messenger RNA | ||||
| Journal or Publication Title: | Plant Signaling & Behavior | ||||
| Publisher: | Landes Bioscience | ||||
| ISSN: | 1559-2316 | ||||
| Official Date: | 2012 | ||||
| Dates: |
|
||||
| Volume: | 7 | ||||
| Number: | 11 | ||||
| Number of Pages: | 4 | ||||
| Page Range: | pp. 1434-1437 | ||||
| DOI: | 10.4161/psb.21960 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Open Access | ||||
| Funder: | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | ||||
| Grant number: | BB/H00775X/1 (BBSRC) |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
