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Cost and quality of life analysis of HIV self-testing and facility-based HIV testing and counselling in Blantyre, Malawi
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Maheswaran, Hendramoorthy, Petrou, Stavros, MacPherson, Peter, Choko, Augustine T., Kumwenda, Felistas, Lalloo, David G., Clarke, Aileen and Corbett, Elizabeth L. (2016) Cost and quality of life analysis of HIV self-testing and facility-based HIV testing and counselling in Blantyre, Malawi. BMC Medicine, 14 (1). pp. 1-12. 34. doi:10.1186/s12916-016-0577-7 ISSN 1741-7015.
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Official URL: http://dx.doi.org/10.1186/s12916-016-0577-7
Abstract
Background:
HIV self-testing (HIVST) has been found to be highly effective, but no cost analysis has been undertaken to guide the design of affordable and scalable implementation strategies.
Methods:
Consecutive HIV self-testers and facility-based testers were recruited from participants in a community cluster-randomised trial (ISRCTN02004005) investigating the impact of offering HIVST in addition to facility-based HIV testing and counselling (HTC). Primary costing studies were undertaken of the HIVST service and of health facilities providing HTC to the trial population. Costs were adjusted to 2014 US$ and INT$. Recruited participants were asked about direct non-medical and indirect costs associated with accessing either modality of HIV testing, and additionally their health-related quality of life was measured using the EuroQol EQ-5D.
Results:
A total of 1,241 participants underwent either HIVST (n = 775) or facility-based HTC (n = 446). The mean societal cost per participant tested through HIVST (US$9.23; 95 % CI: US$9.14-US$9.32) was lower than through facility-based HTC (US$11.84; 95 % CI: US$10.81-12.86). Although the mean health provider cost per participant tested through HIVST (US$8.78) was comparable to facility-based HTC (range: US$7.53-US$10.57), the associated mean direct non-medical and indirect cost was lower (US$2.93; 95 % CI: US$1.90-US$3.96). The mean health provider cost per HIV positive participant identified through HIVST was higher (US$97.50) than for health facilities (range: US$25.18-US$76.14), as was the mean cost per HIV positive individual assessed for anti-retroviral treatment (ART) eligibility and the mean cost per HIV positive individual initiated onto ART. In comparison to the facility-testing group, the adjusted mean EQ-5D utility score was 0.046 (95 % CI: 0.022-0.070) higher in the HIVST group.
Conclusions:
HIVST reduces the economic burden on clients, but is a costlier strategy for the health provider aiming to identify HIV positive individuals for treatment. The provider cost of HIVST could be substantially lower under less restrictive distribution models, or if costs of oral fluid HIV test kits become comparable to finger-prick kits used in health facilities.
Item Type: | Journal Article | ||||||||
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Subjects: | R Medicine > RC Internal medicine | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | HIV infections, HIV-positive persons | ||||||||
Journal or Publication Title: | BMC Medicine | ||||||||
Publisher: | BioMed Central Ltd. | ||||||||
ISSN: | 1741-7015 | ||||||||
Official Date: | 19 February 2016 | ||||||||
Dates: |
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Volume: | 14 | ||||||||
Number: | 1 | ||||||||
Number of Pages: | 12 | ||||||||
Page Range: | pp. 1-12 | ||||||||
Article Number: | 34 | ||||||||
DOI: | 10.1186/s12916-016-0577-7 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||||
Date of first compliant deposit: | 7 April 2016 | ||||||||
Date of first compliant Open Access: | 7 April 2016 | ||||||||
Funder: | Wellcome Trust (London, England) | ||||||||
Grant number: | WT097973 (WT), WT089673 (WT), WT091769 (WT) |
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