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The effectiveness of different interventions to promote poison prevention behaviours in households with children : a network meta-analysis
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Achana, Felix A., Sutton, A. J., Kendrick, D., Wynn, Persephone, Young, Ben, Jones, David R., Hubbard, Stephanie J. and Cooper, Nicola (2015) The effectiveness of different interventions to promote poison prevention behaviours in households with children : a network meta-analysis. PLoS One, 10 (4). pp. 1-18. e0121122. doi:10.1371/journal.pone.0121122 ISSN 1932-6203.
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Official URL: http://dx.doi.org/10.1371/journal.pone.0121122
Abstract
Background
There is evidence from 2 previous meta-analyses that interventions to promote poison prevention behaviours are effective in increasing a range of poison prevention practices in households with children. The published meta-analyses compared any intervention against a “usual care or no intervention” which potentially limits the usefulness of the analysis to decision makers. We aim to use network meta-analysis to simultaneously evaluate the effectiveness of different interventions to increase prevalence of safe storage of i) Medicines only, ii) Other household products only, iii) Poisons (both medicines and non-medicines), iv) Poisonous plants; and v) Possession of poison control centre (PCC) telephone number in households with children.
Methods
Data on the effectiveness of poison prevention interventions was extracted from primary studies identified in 2 newly-undertaken systematic reviews. Effect estimates were pooled across studies using a random effects network meta-analysis model.
Results
28 of the 47 primary studies identified were included in the analysis. Compared to usual care intervention, the intervention with education and low cost/free equipment elements was most effective in promoting safe storage of medicines (odds ratio 2.51, 95% credible interval 1.01 to 6.00) while interventions with education, low cost/free equipment, home safety inspection and fitting components were most effective in promoting safe storage of other household products (2.52, 1.12 to 7.13), safe storage of poisons (11.10, 1.60 to 141.50) and possession of PCC number (38.82, 2.19 to 687.10). No one intervention package was more effective than the others in promoting safe storage of poisonous plants.
Conclusion
The most effective interventions varied by poison prevention practice, but education alone was not the most effective intervention for any poison prevention practice. Commissioners and providers of poison prevention interventions should tailor the interventions they commission or provide to the poison prevention practices they wish to promote.
Item Type: | Journal Article | ||||||||
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Subjects: | R Medicine > R Medicine (General) | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Meta-analysis, Poisons -- Safety measures | ||||||||
Journal or Publication Title: | PLoS One | ||||||||
Publisher: | Public Library of Science | ||||||||
ISSN: | 1932-6203 | ||||||||
Official Date: | 20 April 2015 | ||||||||
Dates: |
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Volume: | 10 | ||||||||
Number: | 4 | ||||||||
Number of Pages: | 18 | ||||||||
Page Range: | pp. 1-18 | ||||||||
Article Number: | e0121122 | ||||||||
DOI: | 10.1371/journal.pone.0121122 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Funder: | National Institute for Health Research (Great Britain) (NIHR) | ||||||||
Grant number: | RP-PG-0407-10231 (NIHR) |
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