Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Cyclic graft copolymer unimolecular micelles : effects of cyclization on particle morphology and thermoresponsive behavior

Tools
- Tools
+ Tools

Williams, Rebecca J., Pitto-Barry, Anaïs, Kirby, Nigel, Dove, Andrew P. and O’Reilly, Rachel K. (2016) Cyclic graft copolymer unimolecular micelles : effects of cyclization on particle morphology and thermoresponsive behavior. Macromolecules, 49 (7). pp. 2802-2813. doi:10.1021/acs.macromol.5b02710

[img]
Preview
PDF
WRAP_acs%2Emacromol%2E5b02710.pdf - Published Version - Requires a PDF viewer.
Available under License Creative Commons Attribution 4.0.

Download (2932Kb) | Preview
Official URL: http://dx.doi.org/10.1021/acs.macromol.5b02710

Request Changes to record.

Abstract

The synthesis of cyclic amphiphilic graft copolymers with a hydrophobic polycarbonate backbone and hydrophilic poly(N-acryloylmorpholine) (PNAM) side arms via a combination of ring-opening polymerization (ROP), cyclization via copper-catalyzed azide–alkyne cycloaddition (CuAAC), and reversible addition–fragmentation chain transfer (RAFT) polymerization is reported. The ability of these cyclic graft copolymers to form unimolecular micelles in water is explored using a combination of light scattering, small-angle X-ray scattering (SAXS), and cryogenic transmission electron microscopy (cryoTEM) analyses, where particle size was found to increase with increasing PNAM arm length. Further analysis revealed differences in the solution conformations, loading capabilities, and morphologies of the cyclic graft copolymers in comparison to equivalent linear graft copolymer unimolecular micelle analogues. Furthermore, the cyclic and linear graft copolymers were found to exhibit significantly different cloud point temperatures. This study highlights how subtle changes in polymer architecture (linear graft copolymer versus cyclic graft copolymer) can dramatically influence a polymer’s nanostructure and its properties.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history
Divisions: Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH): Ring formation (Chemistry) , Chemical reactions, Morphology, Polymerization
Journal or Publication Title: Macromolecules
Publisher: American Chemical Society
ISSN: 0024-9297
Official Date: 17 March 2016
Dates:
DateEvent
17 March 2016Available
15 December 2015Submitted
Volume: 49
Number: 7
Page Range: pp. 2802-2813
DOI: 10.1021/acs.macromol.5b02710
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Royal Society (Great Britain), Engineering and Physical Sciences Research Council (EPSRC), European Research Council (ERC)

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us