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Network meta-analysis to evaluate the effectiveness of interventions to prevent falls in children under age 5 years
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Hubbard, S., Cooper, N., Kendrick, D., Young, B., Wynn, P. M., He, Z., Miller, P., Achana, Felix A. and Sutton, A. (2015) Network meta-analysis to evaluate the effectiveness of interventions to prevent falls in children under age 5 years. Injury Prevention, 21 (2). pp. 98-108. doi:10.1136/injuryprev-2013-041135 ISSN 1353-8047.
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Official URL: http://dx.doi.org/10.1136/injuryprev-2013-041135
Abstract
BACKGROUND:
This study aimed to simultaneously evaluate the effectiveness of a range of interventions to increase the possession of safety equipment or behaviours to prevent falls in children under 5 years of age in the home.
METHODS:
A recently published systematic review identified studies to be included in a network meta-analysis; an extension of pairwise meta-analysis that enables comparison of all evaluated interventions simultaneously, including comparisons not directly compared in individual studies.
RESULTS:
29 primary studies were identified, of which 16 were included in at least 1 of 4 network meta-analyses. For increasing possession of a fitted stair gate, the most intensive intervention (including education, low cost/free home safety equipment, home safety inspection and fitting) was the most likely to be the most effective, with an OR versus usual care of 7.80 (95% CrI 3.08 to 21.3). For reducing possession or use of a baby walker: education only was most likely to be most effective, with an OR versus usual care of 0.48 (95% CrI 0.31 to 0.84). Little difference was found between interventions for possession of window locks (most intensive intervention versus usual care OR=1.56 (95% CrI 0.02 to 89.8)) and for not leaving a child alone on a high surface (education vs usual care OR=0.89 (95% CrI 0.10 to 9.67)). There was insufficient evidence for network meta-analysis for possession and use of bath mats.
CONCLUSIONS:
These results will inform healthcare providers of the most effective components of interventions and can be used in cost-effectiveness analyses.
Item Type: | Journal Article | ||||||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Injury Prevention | ||||||||||
Publisher: | BMJ Group | ||||||||||
ISSN: | 1353-8047 | ||||||||||
Official Date: | April 2015 | ||||||||||
Dates: |
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Volume: | 21 | ||||||||||
Number: | 2 | ||||||||||
Page Range: | pp. 98-108 | ||||||||||
DOI: | 10.1136/injuryprev-2013-041135 | ||||||||||
Status: | Peer Reviewed | ||||||||||
Publication Status: | Published | ||||||||||
Access rights to Published version: | Restricted or Subscription Access |
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