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Effects of probiotics on child growth : a systematic review

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Onubi, Ojochenemi J., Poobalan, Amudha S., Dineen, Brendan, Marais, Debbi and McNeill, Geraldine (2015) Effects of probiotics on child growth : a systematic review. Journal of Health, Population and Nutrition, 34 (8). pp. 1-15. doi:10.1186/s41043-015-0010-4

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Official URL: http://dx.doi.org/10.1186/s41043-015-0010-4

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Abstract

Background:
Child undernutrition has short and long term consequence for both individuals and society. Previous studies show probiotics may promote child growth and have an impact on under-nutrition.

Methods:
A systematic review of the literature was carried out on three electronic databases to assess evidence. The outcome measured was change in weight or height. A narrative analysis was conducted due to heterogeneity of included studies.

Results:
Twelve studies were included in the review of which ten were randomised controlled trials. A total of 2757 children were included, with 1598 from developing countries. The studies varied in type and quantity of probiotics given, duration of interventions, characteristics of participants, setting and units of outcome measures. Overall, five studies found a positive effect of probiotics on child growth. All five were conducted in developing countries with four studies conducted in mostly under-nourished children and one in well-nourished children. No significant effect on growth was found in the seven studies that were conducted in developed countries.

Conclusion:
The limited evidence suggests that probiotics have the potential to improve child growth in developing countries and in under-nourished children. More research is needed to explore this further.

Item Type: Journal Article
Subjects: R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Probiotics, Children -- Growth
Journal or Publication Title: Journal of Health, Population and Nutrition
Publisher: BioMed Central Ltd.
ISSN: 2072-1315
Official Date: 3 May 2015
Dates:
DateEvent
3 May 2015Available
23 July 2014Accepted
UNSPECIFIEDSubmitted
Volume: 34
Number: 8
Number of Pages: 15
Page Range: pp. 1-15
DOI: 10.1186/s41043-015-0010-4
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access

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