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Improving outcomes from in-hospital cardiac arrest
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Couper, Keith and Perkins, Gavin D. (2016) Improving outcomes from in-hospital cardiac arrest. BMJ (Clinical research ed.), 353 . i1858. doi:10.1136/bmj.i1858 ISSN 0959-8138.
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Official URL: http://dx.doi.org/10.1136/bmj.i1858
Abstract
Over 200 000 adults a year sustain a cardiac arrest while in hospital in the United States.1 Most trials have taken place outside hospital,2 yet the aetiology, patient characteristics, time to treatment, and outcomes are quite different to cardiac arrests occurring in inpatients. Clinical guidelines for in-hospital resuscitation are therefore mainly drawn from the extrapolation of findings from out-of-hospital trials, observational studies, and consensus of expert opinion coordinated through the International Liaison Committee for Resuscitation.3
Given the cost, logistical, and ethical challenges of conducting randomised trials in cardiac arrest, the use of high quality observational data to provide insights into the effectiveness of treatments is attractive. The main limitation of observational studies is the risk that the outcome is affected by both the treatment allocation and other factors that influence the treatment allocation. Propensity scoring methods have been growing in popularity as a way of reducing confounding related to measured variables.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RC Internal medicine | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Myocardial infarction -- Hospital patients -- Resuscitation, Cardiac arrest -- Patients -- Treatment, Ventricular fibrillation, CPR (First aid) , Defibrillators, Heart -- Diseases | ||||
Journal or Publication Title: | BMJ (Clinical research ed.) | ||||
Publisher: | B M J Group | ||||
ISSN: | 0959-8138 | ||||
Official Date: | 6 April 2016 | ||||
Dates: |
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Volume: | 353 | ||||
Article Number: | i1858 | ||||
DOI: | 10.1136/bmj.i1858 | ||||
Status: | Not Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Open Access (Creative Commons) | ||||
Date of first compliant deposit: | 17 May 2016 | ||||
Date of first compliant Open Access: | 17 May 2016 |
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