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Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort?
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Thompson, Andrew D., Marwaha, Steven, Nelson, Barnaby, Wood, Stephen J., McGorry, Patrick D., Yung, Alison R. and Lin, Ashleigh (2016) Do affective or dissociative symptoms mediate the association between childhood sexual trauma and transition to psychosis in an ultra-high risk cohort? Psychiatry research, 236 . pp. 182-185. doi:10.1016/j.psychres.2016.01.017 ISSN 0165-1781.
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Official URL: http://dx.doi.org/10.1016/j.psychres.2016.01.017
Abstract
We have previously reported an association between childhood sexual trauma and transition to psychosis in an Ultra High Risk (UHR) population. We aimed to investigate if this association was mediated by affective or dissociative symptoms. Data were from a large UHR for psychosis cohort study. None of the potential mediators (depression, anxiety, dissociation, mood swings and mania, assessed by the HAM-D, HAM-A and the CAARMS symptom scales) significantly mediated the total association between sexual abuse scores and transition. At the point of transition, the mechanistic pathway from sexual trauma to psychosis does not appear to operate through affective symptoms.
Item Type: | Journal Article | ||||||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||||
Journal or Publication Title: | Psychiatry research | ||||||||||
Publisher: | Elsevier Ireland Ltd. | ||||||||||
ISSN: | 0165-1781 | ||||||||||
Official Date: | February 2016 | ||||||||||
Dates: |
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Volume: | 236 | ||||||||||
Page Range: | pp. 182-185 | ||||||||||
DOI: | 10.1016/j.psychres.2016.01.017 | ||||||||||
Status: | Peer Reviewed | ||||||||||
Publication Status: | Published | ||||||||||
Access rights to Published version: | Restricted or Subscription Access |
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