Low infectiousness of a wildlife host of Leishmania infantum: the crab-eating fox is not important for transmission
Courtenay, Orin, Quinnell, R. J., Garcez, L. M. and Dye, C.. (2002) Low infectiousness of a wildlife host of Leishmania infantum: the crab-eating fox is not important for transmission. Parasitology , Vol.12 (No.5). pp. 407-414. ISSN 0031-1820
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Official URL: http://dx.doi.org/10.1017/S0031182002002238
The epidemiological role of the crab-eating fox Cerdocyon thous in the transmission of Leishmania infantum is assessed in a longitudinal study in Amazon Brazil. A total of 37 wild-caught foxes were immunologically and clinically monitored, and 26 foxes exposed to laboratory colonies of the sandfly vector Lutzomyia longipalpis, over a 15-month period. In total 78% (29/37) of foxes were seropositive for anti-Leishmania IgG on at least 1 occasion, and 38% (8/37) had infections confirmed by PCR and/or by culture. Point prevalences were 74% (serology), 15% (PCR), and 26% (culture). No signs of progressive disease were observed. None of the foxes were infectious to the 1469 sandflies dissected from 44 feeds. A conservative estimate of the possible contribution of foxes to transmission was 9% compared to 91% by sympatric domestic dogs. These results show that crab-eating fox populations do not maintain a transmission cycle independently of domestic dogs. The implication is that they are unlikely to introduce the parasite into Leishmania-free dog populations.
|Item Type:||Journal Article|
|Subjects:||Q Science > QL Zoology|
|Divisions:||Faculty of Science > Life Sciences (2010- ) > Biological Sciences ( -2010)|
|Library of Congress Subject Headings (LCSH):||Leishmania, Dusicyon -- Diseases and pests, Kala-azar, Zoonoses, Dogs as carriers of disease|
|Journal or Publication Title:||Parasitology|
|Publisher:||Cambridge University Press|
|Official Date:||May 2002|
|Page Range:||pp. 407-414|
|Access rights to Published version:||Open Access|
001 ALVAR, J., MOLINA, R., SAN ANDRÉS, M., TESOURO, M., NIETO, J., VITUTIA, M., GONZALES, F., SAN ANDRÉS, M. D., BOGGIO, J., RODRIGUEZ, F., SAINZ, A. & ESCACENA, C. (1994). Canine leishmaniasis: clinical, parasitological and entomological follow-up after chemotherapy. Annals of Tropical Medicine and Parasitology 88, 371–378.
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