Courtenay, Orin, Quinnell, R. J., Garcez, L. M. and Dye, C.. (2002) Low infectiousness of a wildlife host of Leishmania infantum: the crab-eating fox is not important for transmission. Parasitology , Vol.12 (No.5). pp. 407-414. ISSN 0031-1820

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Abstract

The epidemiological role of the crab-eating fox Cerdocyon thous in the transmission of Leishmania infantum is assessed in a longitudinal study in Amazon Brazil. A total of 37 wild-caught foxes were immunologically and clinically monitored, and 26 foxes exposed to laboratory colonies of the sandfly vector Lutzomyia longipalpis, over a 15-month period. In total 78% (29/37) of foxes were seropositive for anti-Leishmania IgG on at least 1 occasion, and 38% (8/37) had infections confirmed by PCR and/or by culture. Point prevalences were 74% (serology), 15% (PCR), and 26% (culture). No signs of progressive disease were observed. None of the foxes were infectious to the 1469 sandflies dissected from 44 feeds. A conservative estimate of the possible contribution of foxes to transmission was 9% compared to 91% by sympatric domestic dogs. These results show that crab-eating fox populations do not maintain a transmission cycle independently of domestic dogs. The implication is that they are unlikely to introduce the parasite into Leishmania-free dog populations.

Item Type:	Journal Article
Subjects:	Q Science > QL Zoology
Divisions:	Faculty of Science > Life Sciences (2010- ) > Biological Sciences ( -2010)
Library of Congress Subject Headings (LCSH):	Leishmania, Dusicyon -- Diseases and pests, Kala-azar, Zoonoses, Dogs as carriers of disease
Journal or Publication Title:	Parasitology
Publisher:	Cambridge University Press
ISSN:	0031-1820
Date:	May 2002
Volume:	Vol.12
Number:	No.5
Page Range:	pp. 407-414
Identification Number:	10.1017/S0031182002002238
Status:	Peer Reviewed
Access rights to Published version:	Open Access
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URI:	http://wrap.warwick.ac.uk/id/eprint/795

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