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Delineating noncovalent interactions between the azinomycins and double-stranded DNA: Importance of the naphthalene substitution pattern on interstrand cross-linking efficiency
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UNSPECIFIED. (2004) Delineating noncovalent interactions between the azinomycins and double-stranded DNA: Importance of the naphthalene substitution pattern on interstrand cross-linking efficiency. ORGANIC LETTERS, 6 (20). pp. 3505-3507. ISSN 1523-7060
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Official URL: http://dx.doi.org/10.1021/ol048653y
Abstract
Using a series of synthetic azinomycin analogues, it is shown that the efficiency of in vitro DNA interstrand cross-linking is markedly reduced when either the C-5' methyl group or both the C-5' methyl and C-3' methoxy groups are deleted from the naphthalene ring.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Journal or Publication Title: | ORGANIC LETTERS |
| Publisher: | AMER CHEMICAL SOC |
| ISSN: | 1523-7060 |
| Date: | 30 September 2004 |
| Volume: | 6 |
| Number: | 20 |
| Number of Pages: | 3 |
| Page Range: | pp. 3505-3507 |
| Identification Number: | 10.1021/ol048653y |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/7956 |
Data sourced from Thomson Reuters' Web of Knowledge
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