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Economic and health-related quality of life outcomes of whiplash associated disorders
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Pink, Joshua, Petrou, Stavros, Williamson, Esther M., Williams, M. A. and Lamb, S. E. (Sallie E.) (2016) Economic and health-related quality of life outcomes of whiplash associated disorders. Spine, 41 (17). pp. 1378-1386. ISSN 0362-2436.
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Official URL: http://doi.org/10.1097/BRS.0000000000001512
Abstract
STUDY DESIGN:
This study examines the links between severity of whiplash associated disorder and costs and health outcomes OBJECTIVE.: The aim of this study was to estimate the economic costs and health state utilities associated with disability levels and recovery trajectories following acute whiplash injury.
SUMMARY OF BACKGROUND DATA:
Data used were from the Managing Injuries of the Neck Trial, which collected information on 3,851 people over a 12 month period following acute whiplash injury.
METHODS:
Effects of whiplash associated disorder severity on economic costs (measured from a societal perspective and separately from a health and personal social services perspective) were estimated using two-part regression models, comprising probability of incurring a cost and the total cost, given one was incurred. Effects on health state utilities (measured using the EQ-5D and SF-6D) were estimated using ordinary least squares regression, and two-part models as for costs.
RESULTS:
There was a direct relationship between severity of disability following acute whiplash injury and economic costs. Between baseline and 4 months, average societal costs for those with no disability were £99.55 (UK£, 2009 prices), increasing to £668.53 for those with complete disability. Average societal costs for the whole sample were £234.15 over the first 4 months, decreasing to £127.51 between 8 and 12 months. Conversely, utility scores decreased with increased disability. The average EQ-5D utility score was 0.934 at 4 months for those with no disability, decreasing to 0.033 for those with complete disability. The average EQ-5D utility score for the whole sample increased from 0.587 immediately post-injury to 0.817 at 12 months. Relative costs and disutilities generated by the multivariate models are also presented by disability level and recovery trajectory.
CONCLUSIONS:
These results provide estimates of the costs and health state utilities associated with disability levels and recovery trajectories following acute whiplash injury. They can be used to inform estimates of the cost-effectiveness of interventions targeting whiplash associated disorders.
Item Type: | Journal Article | ||||||
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Subjects: | R Medicine > RD Surgery | ||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Whiplash injuries -- Economic aspects, Whiplash injuries -- Social aspects, Disabilities , Traffic accidents -- Health aaspects | ||||||
Journal or Publication Title: | Spine | ||||||
Publisher: | Lippincott Williams & Wilkins | ||||||
ISSN: | 0362-2436 | ||||||
Official Date: | September 2016 | ||||||
Dates: |
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Volume: | 41 | ||||||
Number: | 17 | ||||||
Page Range: | pp. 1378-1386 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||
Date of first compliant deposit: | 26 January 2017 | ||||||
Date of first compliant Open Access: | 23 February 2017 | ||||||
Funder: | Birmingham Science City, Advantage West Midlands (AWM), Wolfson Foundation (WF), National Institute for Health Research Health Technology Assessment (Great Britain) (NIHR HTA), Oxford Biomedical Research Centre | ||||||
Grant number: | Project number 02/35/02 (NIHR HTA) |
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