Leng, Y., Wainwright, N. W. J., Cappuccio, Francesco, Surtees , P. G., Hayat, S., Luben, R., Brayne, C. and Khaw, K. T. (2016) Daytime napping and increased risk of incident respiratory diseases : symptom, marker or risk factor? Sleep Medicine, 23 . pp. 12-15. doi:10.1016/j.sleep.2016.06.012 ISSN 1389-9457.

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Abstract

Background: We have identified a strong association between daytime napping and increased mortality risk from respiratory diseases, but little is known about the relationship between daytime napping and respiratory morbidity.
Methods: Data were drawn from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort. Participants reported napping habits during 1998-2000, and were followed up for respiratory disease hospital admissions until March 2009. Cox proportional hazards regression was used to examine the association between daytime napping and respiratory disease incidence risk.
Results: The study sample included 10978 men and women with a mean age of 61.9 years old, and a total of 946 incident respiratory disease cases were recorded. After adjustment for age, sex, social class, education, marital status, employment status, nightshift work, body mass index (BMI), physical activity, smoking, alcohol intake, self-reported general health, hypnotic drug use, habitual sleep duration and pre-existing health conditions, daytime napping was associated with an increase in the overall respiratory incidence risk [Hazard Ratio (HR) =1.32, 95% confidence interval (CI) 1.15, 1.52 for napping<1h; HR=1.54, 95% CI 1.14, 2.09 for napping≥1h]. This association was more pronounced for lower respiratory diseases, especially for the risk of chronic lower respiratory diseases (HR = 1.52, 95% CI: 1.18, 1.96 for napping <1h; HR = 1.72, 95% CI: 1.01, 2.92 for napping≥1h, overall p=0.003).
Conclusions: Excessive daytime napping might be a useful indicator of future respiratory incidence risk. Further studies are required to confirm these findings and help understand potential mechanisms.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Naps (Sleep) , Respiratory organs -- Diseases -- Diagnosis
Journal or Publication Title:	Sleep Medicine
Publisher:	Elsevier BV
ISSN:	1389-9457
Official Date:	July 2016
Dates:	Date Event July 2016 Published 12 July 2016 Available 30 June 2016 Accepted
Volume:	23
Page Range:	pp. 12-15
DOI:	10.1016/j.sleep.2016.06.012
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access (Creative Commons)
Date of first compliant deposit:	4 July 2016
Date of first compliant Open Access:	29 September 2016
Funder:	Medical Research Council (Great Britain) (MRC), Cancer Research UK (CRUK)
Grant number:	G9502233 and G1000143 (MRC), SP2024/0204 and C864/A14136 (CRUK)

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