Coulthard, E., Rudd, A., Playford, E. Diane and Husain, M. (2007) Alien limb following posterior cerebral artery stroke : failure to recognise internally generated movements. Movement Disorders, 22 (10). pp. 1498-1502. doi:DOI: 10.1002/mds.21546 ISSN 0885-3185.

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Abstract

We describe two rare cases of alien limb syndrome following right posterior cerebral artery (PCA) stroke. Both patients present with left hemianopia, visual neglect and proprioceptive loss in addition to their alien limb symptoms. Lesion subtraction from seven control PCA cases revealed that medial parietal-occipital and thalamic areas were selectively damaged in the alien limb patients. We propose that loss of the sense of motor intention and internal model of the current state of the arm, combined with deficient proprioceptive and visual feedback of the moving limb, are critical for genesis of posterior alien limb and discuss how affected regions normally function to ensure awareness of self-generated motor activity.

Item Type:	Journal Article
Divisions:	Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Social Science & Systems in Health (SSSH) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title:	Movement Disorders
Publisher:	Wiley-Blackwell Publishing Ltd.
ISSN:	0885-3185
Official Date:	2007
Dates:	Date Event 2007 Published
Volume:	22
Number:	10
Page Range:	pp. 1498-1502
DOI:	DOI: 10.1002/mds.21546
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Related URLs:	Other

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