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Evaluation of cognitive assessment and cognitive intervention for people with multiple sclerosis

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Lincoln, N. B., Dent, A., Harding, J., Weyman, N., Nicholl, C., Blumhardt, L. D. and Playford, E. Diane (2002) Evaluation of cognitive assessment and cognitive intervention for people with multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 72 . pp. 93-98. doi:10.1136/jnnp.72.1.93 ISSN 0022-3050.

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Official URL: http://dx.doi.org/10.1136/jnnp.72.1.93

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Abstract

Objectives: Cognitive problems in multiple sclerosis are common but any possible benefits of treatment remain uncertain. The aim of the study was to evaluate the benefits of providing a psychology service, including cognitive assessment and intervention, to patients with multiple sclerosis.

Method: The study was a single blind randomised controlled trial. A total of 240 patients with clinically definite, laboratory supported, or clinically probable multiple sclerosis were recruited from an multiple sclerosis management clinic and assessed on a brief screening battery. They were randomised into three groups. The control group received no further intervention. The assessment group received a detailed cognitive assessment, the result of which was fed back to staff involved in the patients' care. The treatment group received the same detailed cognitive assessment and a treatment programme designed to help reduce the impact of their cognitive problems. Patients were followed up 4 and 8 months later on the general health questionnaire (GHQ-28), extended activities of daily living scale, SF-36, everyday memory questionnaire, dysexecutive syndrome questionnaire, and memory aids questionnaire.

Results: The three groups were compared on the outcome measures at 4 and 8 months after recruitment. There were few significant differences between the groups and those that occurred favoured the control group. Overall, the results showed no effect of the interventions on mood, quality of life, subjective cognitive impairment or independence.

Conclusions: The study failed to detect any significant effects of cognitive assessment or cognitive intervention in this cohort of people with multiple sclerosis.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Social Science & Systems in Health (SSSH)
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Journal of Neurology, Neurosurgery and Psychiatry
Publisher: B M J Group
ISSN: 0022-3050
Official Date: 2002
Dates:
DateEvent
2002Published
Volume: 72
Page Range: pp. 93-98
DOI: 10.1136/jnnp.72.1.93
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
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