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In vivo and vitro studies of the dopaminergic system in movement disorders
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Playford, E. Diane and Brooks, D. J. (1992) In vivo and vitro studies of the dopaminergic system in movement disorders. Cerebrovascular and Brain Metabolism Reviews, 4 (2). pp. 144-171. ISSN 1040-8827.
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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/1627440
Abstract
Over the past 20 years, tritiated radioligand receptor binding has been used to study the relationship between dopamine receptor binding and various movement disorders, in particular Parkinson disease. More recently, in vivo imaging techniques like positron emission tomography and single photon emission computed tomography have been used to study the dopaminergic system in these disorders. This review describes the data that have been obtained using in vivo and in vitro measurements of the dopaminergic system in movement disorders, and examines the relationship between them. The contribution of these techniques to clinical management is described.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Social Science & Systems in Health (SSSH) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Cerebrovascular and Brain Metabolism Reviews | ||||
| Publisher: | Lippincott - Raven Publishers | ||||
| ISSN: | 1040-8827 | ||||
| Official Date: | 1992 | ||||
| Dates: |
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| Volume: | 4 | ||||
| Number: | 2 | ||||
| Page Range: | pp. 144-171 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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