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Depression and schizophrenia : cause, consequence or trans-diagnostic issue?
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Upthegrove, Rachel, Marwaha, Steven and Birchwood, M. J. (2017) Depression and schizophrenia : cause, consequence or trans-diagnostic issue? Schizophrenia Bulletin, 43 (2). pp. 240-244. doi:10.1093/schbul/sbw097 ISSN 0586-7614.
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Official URL: https://doi.org/10.1093/schbul/sbw097
Abstract
The presence of depression in schizophrenia has been a challenge to the Kraepelinian dichotomy, with various attempts to save the fundamental distinction including evoking and refining diagnoses such as schizoaffective disorder. But the tectonic plates are shifting. Here we put forward a summary of recent evidence regarding the prevalence, importance, possible aetiological pathways and treatment challenges that recognising depression in schizophrenia bring. Taken together we propose that depression is more than co-morbidity and that increased effective therapeutic attention to mood symptoms will be needed to improve outcomes and to support prevention.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RC Internal medicine | ||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Schizophrenia, Depression, Mental | ||||||||
| Journal or Publication Title: | Schizophrenia Bulletin | ||||||||
| Publisher: | Oxford University Press | ||||||||
| ISSN: | 0586-7614 | ||||||||
| Official Date: | 1 March 2017 | ||||||||
| Dates: |
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| Volume: | 43 | ||||||||
| Number: | 2 | ||||||||
| Page Range: | pp. 240-244 | ||||||||
| DOI: | 10.1093/schbul/sbw097 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||
| Date of first compliant deposit: | 5 July 2016 | ||||||||
| Date of first compliant Open Access: | 15 July 2017 | ||||||||
| Funder: | National Institute for Health Research (Great Britain) (NIHR) | ||||||||
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