UNSPECIFIED (2004) The detection of circulating breast cancer cells in blood. JOURNAL OF CLINICAL PATHOLOGY, 57 (9). pp. 903-911. ISSN 0021-9746

Full text not available from this repository.

Abstract

At present, sampling of the lymph nodes or bone marrow for the detection of regions of metastatic disease in patients with breast cancer can only be undertaken at the time of initial diagnosis and surgery. However, the sampling of these tissues and the methods used are inaccurate, time consuming, and cannot be used for easy routine screening to determine disease recurrence and response to treatment. Because of the problems encountered with current methods and tissues sampled at the time of breast cancer diagnosis, this review discusses the urgent requirement for and potential development of a quick, simple, and accurate diagnostic test utilising the haematogenous system, a source of circulating tumour cells in patients with breast cancer, and highly sensitive molecular biological techniques, such as reverse transcription polymerase chain reaction. In addition, this review also highlights potential problems that may be encountered and should be avoided when devising such a test.

Item Type:	Journal Item
Subjects:	R Medicine > RB Pathology
Journal or Publication Title:	JOURNAL OF CLINICAL PATHOLOGY
Publisher:	B M J PUBLISHING GROUP
ISSN:	0021-9746
Date:	September 2004
Volume:	57
Number:	9
Number of Pages:	9
Page Range:	pp. 903-911
Identification Number:	10.1136/jcp.2003.013755
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/8097

Data sourced from Thomson Reuters' Web of Knowledge

Request changes to a record

Actions (login required)

View Item