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Corticotropin releasing factor (CRF) peptide family and their receptors: Divergent actions influencing human physiology
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UNSPECIFIED (2004) Corticotropin releasing factor (CRF) peptide family and their receptors: Divergent actions influencing human physiology. [Journal Item]
Full text not available from this repository.Abstract
Corticotropin-releasing factor (CRF) and its related peptides play a central role in the co-ordination of autonomic. behavioural. cardiovascular, immune and endocrine responses to stressful stimuli. Their actions are mediated through activation of two G-protein-coupled receptors encoded by separate genes, termed CRF-R1 and -R2. In this review we focus on the structure, phylogeny, and expression of CRF peptide family. We present up-to-date literature on divergent actions of the CRF peptide family, including stress and behaviour, cardiovascular physiology, energy balance and reproduction. We also present a brief overview of CRF receptors including pharmacological aspects and potential therapeutic interventions for CRF receptors.
| Item Type: | Journal Item |
|---|---|
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH426 Genetics |
| Journal or Publication Title: | CURRENT GENOMICS |
| Publisher: | BENTHAM SCIENCE PUBL LTD |
| ISSN: | 1389-2029 |
| Date: | August 2004 |
| Volume: | 5 |
| Number: | 6 |
| Number of Pages: | 9 |
| Page Range: | pp. 473-481 |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/8121 |
Data sourced from Thomson Reuters' Web of Knowledge
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