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Adherence to antiretroviral therapy among HIV-infected prisoners : a systematic review and meta-analysis

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Uthman, Olalekan A., Oladimeji, Olanrewaju and Nduka, Chidozie U. (2017) Adherence to antiretroviral therapy among HIV-infected prisoners : a systematic review and meta-analysis. AIDS Care, 29 (4). pp. 489-497. doi:10.1080/09540121.2016.1223799 ISSN 0954-0121.

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Official URL: http://dx.doi.org/10.1080/09540121.2016.1223799

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Abstract

Data on antiretroviral therapy (ART) adherence among prison inmates are limited and not previously synthesized in a systematic manner. The objective of this study was to provide accurate and up-to-date ART adherence estimates among prison inmates. We searched electronic databases for all studies reporting adherence as a primary or secondary outcome among prison inmates. A random-effects model was used to pool adherence rates; sensitivity, heterogeneity and publication bias were assessed. Eleven studies involving 2895 HIV-infected prison inmates were included. The studies were carried out between 1992 and 2011 and reported between 1998 and 2013. A pooled analysis of all studies indicated a pooled estimate of 54.6% (95% confidence interval 48.1–60.9%) of prison inmates had adequate (≥95%) ART adherence. The adherence estimates were significantly higher among cross-studies and studies that used self-reported measures. In summary, our findings indicate that optimal adherence remains a challenge among prison inmates. It is crucial to monitor ART adherence and develop appropriate interventions to improve adherence among these population.

Item Type: Journal Article
Subjects: H Social Sciences > HV Social pathology. Social and public welfare
R Medicine > RA Public aspects of medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): HIV infections, HIV-positive persons, Prisoners -- Medical care , Prisons , Systematic reviews (Medical research)
Journal or Publication Title: AIDS Care
Publisher: Taylor and Francis
ISSN: 0954-0121
Official Date: 2017
Dates:
DateEvent
2017Published
1 September 2016Available
9 August 2016Accepted
27 April 2016Submitted
Volume: 29
Number: 4
Page Range: pp. 489-497
DOI: 10.1080/09540121.2016.1223799
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 6 September 2016
Date of first compliant Open Access: 1 September 2017

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