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Adherence to antiretroviral therapy among HIV-infected prisoners : a systematic review and meta-analysis
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Uthman, Olalekan A., Oladimeji, Olanrewaju and Nduka, Chidozie U. (2017) Adherence to antiretroviral therapy among HIV-infected prisoners : a systematic review and meta-analysis. AIDS Care, 29 (4). pp. 489-497. doi:10.1080/09540121.2016.1223799 ISSN 0954-0121.
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Official URL: http://dx.doi.org/10.1080/09540121.2016.1223799
Abstract
Data on antiretroviral therapy (ART) adherence among prison inmates are limited and not previously synthesized in a systematic manner. The objective of this study was to provide accurate and up-to-date ART adherence estimates among prison inmates. We searched electronic databases for all studies reporting adherence as a primary or secondary outcome among prison inmates. A random-effects model was used to pool adherence rates; sensitivity, heterogeneity and publication bias were assessed. Eleven studies involving 2895 HIV-infected prison inmates were included. The studies were carried out between 1992 and 2011 and reported between 1998 and 2013. A pooled analysis of all studies indicated a pooled estimate of 54.6% (95% confidence interval 48.1–60.9%) of prison inmates had adequate (≥95%) ART adherence. The adherence estimates were significantly higher among cross-studies and studies that used self-reported measures. In summary, our findings indicate that optimal adherence remains a challenge among prison inmates. It is crucial to monitor ART adherence and develop appropriate interventions to improve adherence among these population.
Item Type: | Journal Article | ||||||||||
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Subjects: | H Social Sciences > HV Social pathology. Social and public welfare R Medicine > RA Public aspects of medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||||
Library of Congress Subject Headings (LCSH): | HIV infections, HIV-positive persons, Prisoners -- Medical care , Prisons , Systematic reviews (Medical research) | ||||||||||
Journal or Publication Title: | AIDS Care | ||||||||||
Publisher: | Taylor and Francis | ||||||||||
ISSN: | 0954-0121 | ||||||||||
Official Date: | 2017 | ||||||||||
Dates: |
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Volume: | 29 | ||||||||||
Number: | 4 | ||||||||||
Page Range: | pp. 489-497 | ||||||||||
DOI: | 10.1080/09540121.2016.1223799 | ||||||||||
Status: | Peer Reviewed | ||||||||||
Publication Status: | Published | ||||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||||
Date of first compliant deposit: | 6 September 2016 | ||||||||||
Date of first compliant Open Access: | 1 September 2017 |
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