Uthman, Olalekan A., Oladimeji, Olanrewaju and Nduka, Chidozie U. (2017) Adherence to antiretroviral therapy among HIV-infected prisoners : a systematic review and meta-analysis. AIDS Care, 29 (4). pp. 489-497. doi:10.1080/09540121.2016.1223799

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Abstract

Data on antiretroviral therapy (ART) adherence among prison inmates are limited and not previously synthesized in a systematic manner. The objective of this study was to provide accurate and up-to-date ART adherence estimates among prison inmates. We searched electronic databases for all studies reporting adherence as a primary or secondary outcome among prison inmates. A random-effects model was used to pool adherence rates; sensitivity, heterogeneity and publication bias were assessed. Eleven studies involving 2895 HIV-infected prison inmates were included. The studies were carried out between 1992 and 2011 and reported between 1998 and 2013. A pooled analysis of all studies indicated a pooled estimate of 54.6% (95% confidence interval 48.1–60.9%) of prison inmates had adequate (≥95%) ART adherence. The adherence estimates were significantly higher among cross-studies and studies that used self-reported measures. In summary, our findings indicate that optimal adherence remains a challenge among prison inmates. It is crucial to monitor ART adherence and develop appropriate interventions to improve adherence among these population.

Item Type:	Journal Article
Subjects:	H Social Sciences > HV Social pathology. Social and public welfare R Medicine > RA Public aspects of medicine
Divisions:	Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	HIV infections, HIV-positive persons, Prisoners -- Medical care , Prisons , Systematic reviews (Medical research)
Journal or Publication Title:	AIDS Care
Publisher:	Taylor and Francis
ISSN:	0954-0121
Official Date:	2017
Dates:	Date Event 2017 Published 1 September 2016 Available 9 August 2016 Accepted 27 April 2016 Submitted
Date of first compliant deposit:	6 September 2016
Volume:	29
Number:	4
Page Range:	pp. 489-497
DOI:	10.1080/09540121.2016.1223799
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access

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