Hsueh, Nathanael, Clarkson, Guy J. and Shipman, Michael (2016) Functionalization of alkenes through telescoped continuous flow aziridination processes. Organic Letters, 18 (9). pp. 4908-4911. doi:10.1021/acs.orglett.6b02349

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Abstract

Alkenes can be efficiently aziridinated using highly soluble iminoiodane derivatives under continuous flow conditions. By combining the aziridine generation with nucleophilic ring opening reactions, a variety of products can be made without the need to handle or isolate these potentially hazardous intermediates. Additionally, this chemistry can be used to make and use aziridines that are difficult to isolate and purify because of their high reactivity.

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH):	Alkenes, Aziridines
Journal or Publication Title:	Organic Letters
Publisher:	American Chemical Society
ISSN:	1523-7060
Official Date:	7 October 2016
Dates:	Date Event 7 October 2016 Published 13 September 2016 Available 8 September 2016 Accepted
Volume:	18
Number:	9
Page Range:	pp. 4908-4911
DOI:	10.1021/acs.orglett.6b02349
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	University of Warwick, Birmingham Science City
Version or Related Resource:	http://wrap.warwick.ac.uk/93202/

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