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Functionalization of alkenes through telescoped continuous flow aziridination processes
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Hsueh, Nathanael, Clarkson, Guy J. and Shipman, Michael (2016) Functionalization of alkenes through telescoped continuous flow aziridination processes. Organic Letters, 18 (9). pp. 4908-4911. doi:10.1021/acs.orglett.6b02349
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Official URL: https://doi.org/10.1021/acs.orglett.6b02349
Abstract
Alkenes can be efficiently aziridinated using highly soluble iminoiodane derivatives under continuous flow conditions. By combining the aziridine generation with nucleophilic ring opening reactions, a variety of products can be made without the need to handle or isolate these potentially hazardous intermediates. Additionally, this chemistry can be used to make and use aziridines that are difficult to isolate and purify because of their high reactivity.
Item Type: | Journal Article | ||||||||
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Subjects: | Q Science > QD Chemistry | ||||||||
Divisions: | Faculty of Science > Chemistry | ||||||||
Library of Congress Subject Headings (LCSH): | Alkenes, Aziridines | ||||||||
Journal or Publication Title: | Organic Letters | ||||||||
Publisher: | American Chemical Society | ||||||||
ISSN: | 1523-7060 | ||||||||
Official Date: | 7 October 2016 | ||||||||
Dates: |
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Volume: | 18 | ||||||||
Number: | 9 | ||||||||
Page Range: | pp. 4908-4911 | ||||||||
DOI: | 10.1021/acs.orglett.6b02349 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||||
Funder: | University of Warwick, Birmingham Science City | ||||||||
Version or Related Resource: | http://wrap.warwick.ac.uk/93202/ |
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