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Has metal-on-metal resurfacing been a cost-effective intervention for health care providers? - a registry based study

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Pulikottil-Jacob, Ruth, Connock, M., Ngianga-Bakwin, Kandala, Mistry, Hema, Grove, Amy L., Freeman, Karoline, Costa, Matthew L., Sutcliffe, P. (Paul) and Clarke, Aileen (2016) Has metal-on-metal resurfacing been a cost-effective intervention for health care providers? - a registry based study. PLoS One, 11 (11). e0165021.

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Official URL: http://dx.doi.org/10.1371/journal.pone.0165021

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Abstract

Background: Total hip replacement for end stage arthritis of the hip is currently the most common elective surgical procedure. In 2007 about 7.5% of UK implants were metal-on-metal joint resurfacing (MoM RS) procedures. Due to poor revision performance and concerns about metal debris, the use of RS had declined by 2012 to about a 1% share of UK hip procedures. This study estimated the lifetime cost-effectiveness of metal-on-metal resurfacing (RS) procedures versus commonly employed total hip replacement (THR) methods.

Methodology/Principal Findings: We performed a cost-utility analysis using a well-established multi-state semi-Markov model from an NHS and personal and social services perspective. We used individual patient data (IPD) from the National Joint Registry (NJR) for England and Wales on RS and THR surgery for osteoarthritis recorded from April 2003 to December 2012. We used flexible parametric modelling of NJR RS data to guide identification of patient subgroups and RS devices which delivered revision rates within the NICE 5% revision rate benchmark at 10 years. RS procedures overall have an estimated revision rate of 13% at 10 years, compared to <4% for most THR devices. New NICE guidance now recommends a revision rate benchmark of <5% at 10 years. 60% of RS implants in men and 2% in women were predicted to be within the revision benchmark. RS devices satisfying the 5% benchmark were unlikely to be cost-effective compared to THR at a standard UK willingness to pay of £20,000 per quality-adjusted life-year. However, the probability of cost effectiveness was sensitive to small changes in the costs of devices or in quality of life or revision rate estimates.

Conclusion/Significance: Our results imply that in most cases RS has not been a cost-effective resource and should probably not be adopted by decision makers concerned with the cost effectiveness of hip replacement, or by patients concerned about the likelihood of revision, regardless of patient age or gender.

Item Type: Journal Article
Subjects: R Medicine > RD Surgery
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET)
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Total hip replacement -- Cost effectiveness , Osteoarthritis -- Treatment
Journal or Publication Title: PLoS One
Publisher: Public Library of Science
ISSN: 1932-6203
Official Date: 1 November 2016
Dates:
DateEvent
1 November 2016Published
6 October 2016Accepted
Date of first compliant deposit: 19 December 2016
Volume: 11
Number: 11
Article Number: e0165021
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
Funder: Health Technology Assessment (HTA) Programme
Grant number: Project number 11/118

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