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Multiple risk factor interventions for primary prevention of cardiovascular disease in LMIC : a Cochrane Review
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Uthman, Olalekan A., Hartley, Louise, Rees, Karen, Taylor, Fiona, Ebrahim, Shah and Clarke, Aileen (2017) Multiple risk factor interventions for primary prevention of cardiovascular disease in LMIC : a Cochrane Review. Global Heart, 12 (3). 199-208.e8. doi:10.1016/j.gheart.2016.03.639 ISSN 2211-8179.
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Official URL: http://dx.doi.org/10.1016/j.gheart.2016.03.639
Abstract
This study sought to determine the effectiveness of multiple risk factor interventions aimed at modifying major cardiovascular risk factors for the primary prevention of cardiovascular disease in low- and middle-income countries (LMIC). We searched electronic databases for randomized controlled trials of health promotion interventions to achieve behavior change. The pooled effect indicated a reduction in systolic blood pressure (-6.72 mm Hg; 95% confidence interval [CI]: -9.82 to -3.61; I(2) = 91%), diastolic blood pressure (-4.40 mm Hg; 95% CI: -6.47 to -2.34; I(2) = 92%), body mass index (-0.76 kg/m(2); 95% CI: -1.29 to -0.22; I(2) = 80%), and waist circumference (-3.31 cm; 95% CI: -4.77 to -1.86; I(2) = 55%) in favor of multiple risk factor interventions. There is some evidence that multiple risk factor interventions may lower blood pressure levels and anthropometrics in populations in LMIC settings at high risk of hypertension and diabetes.
| Item Type: | Journal Article | ||||||||||
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||||
| Journal or Publication Title: | Global Heart | ||||||||||
| Publisher: | Elsevier | ||||||||||
| ISSN: | 2211-8179 | ||||||||||
| Official Date: | September 2017 | ||||||||||
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| Volume: | 12 | ||||||||||
| Number: | 3 | ||||||||||
| Page Range: | 199-208.e8 | ||||||||||
| DOI: | 10.1016/j.gheart.2016.03.639 | ||||||||||
| Status: | Peer Reviewed | ||||||||||
| Publication Status: | Published | ||||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||||
| Description: | This review is an abridged version of a previously published Cochrane review: Uthman OA, Hartley L, Rees K, Taylor F, Ebrahim S, Clarke A. Multiple risk factor interventions for primary prevention of cardiovascular disease in low- and middle-income countries. Cochrane Database of Systematic Reviews 2015;(8):CD011163, http://dx.doi.org/10.1002/14651858.CD011163.pub2 (see www.thecochranelibrary.com for information). Cochrane reviews are regularly updated as new evidence emerges and in response to feedback, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the review. |
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