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Radiation therapy variation in the Randomized Phase 3 Positron Emission Tomography Neck Study
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Hartley, A., Fong, C., Sanghera, P., Wong, W. L., McConkey, Christopher C., Rahman, J., Nutting, C. M., Al-Booz, H., Robinson, M., Junor, E., Rizwanullah, M., Dunn, Janet A. and Mehanna, H. (2016) Radiation therapy variation in the Randomized Phase 3 Positron Emission Tomography Neck Study. International Journal of Radiation Oncology Biology Physics, 96 (2). S117. doi:10.1016/j.ijrobp.2016.06.285
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Official URL: http://dx.doi.org/10.1016/j.ijrobp.2016.06.285
Abstract
Five hundred sixty-four patients with squamous cell carcinoma of the head and neck receiving definitive chemoradiation in the PET Neck phase 3 trial were randomized to either planned neck dissection or PETCT scan guided surveillance. The primary endpoint for this study has been previously reported. As the trial spanned the period of IMRT introduction in the United Kingdom, a pragmatic approach to radiotherapy fractionation and technique was adopted and thus three-dimensional conformal radiotherapy (3D-CRT) or intensity modulated radiotherapy (IMRT) were permitted as were 4, 6, or 7 week radiotherapy schedules.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
| Journal or Publication Title: | International Journal of Radiation Oncology Biology Physics | ||||
| Publisher: | Elsevier | ||||
| ISSN: | 0360-3016 | ||||
| Official Date: | 1 September 2016 | ||||
| Dates: |
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| Volume: | 96 | ||||
| Number: | 2 | ||||
| Page Range: | S117 | ||||
| DOI: | 10.1016/j.ijrobp.2016.06.285 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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