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Place cells and long-term potentiation in the hippocampus

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Cobar, Luis Fernando, Yuan, Li and Tashiro, Ayumu (2017) Place cells and long-term potentiation in the hippocampus. Neurobiology of Learning and Memory, 138 . pp. 206-214. doi:10.1016/j.nlm.2016.10.010 ISSN 1074-7427.

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Official URL: http://dx.doi.org/10.1016/j.nlm.2016.10.010

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Abstract

Place cells show location-specific firing patterns according to an animal’s position in an environment and are thought to contribute to the spatial representation required for self-navigation. Decades of study have extensively characterized the properties of place cells and suggested the involvement of long-term potentiation (LTP), a long-lasting synaptic strengthening, in place cell activity. Here, we review the basic characteristics of place cell activity and the findings that support the idea that LTP contributes to the formation, maintenance, and plasticity of place cell activity.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Journal or Publication Title: Neurobiology of Learning and Memory
Publisher: Academic Press
ISSN: 1074-7427
Official Date: February 2017
Dates:
DateEvent
February 2017Published
26 October 2016Available
21 October 2016Accepted
29 April 2016Submitted
Volume: 138
Page Range: pp. 206-214
DOI: 10.1016/j.nlm.2016.10.010
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
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