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Place cells and long-term potentiation in the hippocampus
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Cobar, Luis Fernando, Yuan, Li and Tashiro, Ayumu (2017) Place cells and long-term potentiation in the hippocampus. Neurobiology of Learning and Memory, 138 . pp. 206-214. doi:10.1016/j.nlm.2016.10.010
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Official URL: http://dx.doi.org/10.1016/j.nlm.2016.10.010
Abstract
Place cells show location-specific firing patterns according to an animal’s position in an environment and are thought to contribute to the spatial representation required for self-navigation. Decades of study have extensively characterized the properties of place cells and suggested the involvement of long-term potentiation (LTP), a long-lasting synaptic strengthening, in place cell activity. Here, we review the basic characteristics of place cell activity and the findings that support the idea that LTP contributes to the formation, maintenance, and plasticity of place cell activity.
| Item Type: | Journal Article | ||||||||||
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| Divisions: | Faculty of Science > Life Sciences (2010- ) | ||||||||||
| Journal or Publication Title: | Neurobiology of Learning and Memory | ||||||||||
| Publisher: | Academic Press | ||||||||||
| ISSN: | 1074-7427 | ||||||||||
| Official Date: | February 2017 | ||||||||||
| Dates: |
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| Volume: | 138 | ||||||||||
| Page Range: | pp. 206-214 | ||||||||||
| DOI: | 10.1016/j.nlm.2016.10.010 | ||||||||||
| Status: | Peer Reviewed | ||||||||||
| Publication Status: | Published | ||||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||||
| Adapted As: |
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