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Epstein–Barr virus : more than 50 years old and still providing surprises

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Young, Lawrence S., Yap, Lee Fah and Murray, Paul G. (2016) Epstein–Barr virus : more than 50 years old and still providing surprises. Nature Reviews Cancer, 16 (12). pp. 789-802. doi:10.1038/nrc.2016.92 ISSN 1474-175X.

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Official URL: http://dx.doi.org/10.1038/nrc.2016.92

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Abstract

It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was discovered. EBV has subsequently been found to be associated with a diverse range of tumours of both lymphoid and epithelial origin. Progress in the molecular analysis of EBV has revealed fundamental mechanisms of more general relevance to the oncogenic process. This Timeline article highlights key milestones in the 50-year history of EBV and discusses how this virus provides a paradigm for exploiting insights at the molecular level in the diagnosis, treatment and prevention of cancer.

Item Type: Journal Article
Divisions: Administration > University Executive Office
Journal or Publication Title: Nature Reviews Cancer
Publisher: Nature Publishing Group
ISSN: 1474-175X
Official Date: 30 September 2016
Dates:
DateEvent
30 September 2016Available
Volume: 16
Number: 12
Page Range: pp. 789-802
DOI: 10.1038/nrc.2016.92
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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