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Epstein–Barr virus : more than 50 years old and still providing surprises
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Young, Lawrence S., Yap, Lee Fah and Murray, Paul G. (2016) Epstein–Barr virus : more than 50 years old and still providing surprises. Nature Reviews Cancer, 16 (12). pp. 789-802. doi:10.1038/nrc.2016.92
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Official URL: http://dx.doi.org/10.1038/nrc.2016.92
Abstract
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was discovered. EBV has subsequently been found to be associated with a diverse range of tumours of both lymphoid and epithelial origin. Progress in the molecular analysis of EBV has revealed fundamental mechanisms of more general relevance to the oncogenic process. This Timeline article highlights key milestones in the 50-year history of EBV and discusses how this virus provides a paradigm for exploiting insights at the molecular level in the diagnosis, treatment and prevention of cancer.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Administration > University Executive Office | ||||
| Journal or Publication Title: | Nature Reviews Cancer | ||||
| Publisher: | Nature Publishing Group | ||||
| ISSN: | 1474-175X | ||||
| Official Date: | 30 September 2016 | ||||
| Dates: |
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| Volume: | 16 | ||||
| Number: | 12 | ||||
| Page Range: | pp. 789-802 | ||||
| DOI: | 10.1038/nrc.2016.92 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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