Protein adaptation : mitotic functions for membrane trafficking proteins

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Abstract

Membrane trafficking and mitosis are two essential processes in eukaryotic cells. Surprisingly, many proteins best known for their role in membrane trafficking have additional 'moonlighting' functions in mitosis. Despite having proteins in common, there is insufficient evidence for a specific connection between these two processes. Instead, these phenomena demonstrate the adaptability of the membrane trafficking machinery that allows its repurposing for different cellular functions.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Cell & Developmental Biology
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Nature Reviews Molecular Cell Biology
Publisher: Nature Publishing Group
ISSN: 1471-0072
Official Date: September 2013
Dates:
Date
Event
September 2013
Published
14 August 2013
Available
Volume: 14
Number: 9
Page Range: pp. 592-599
DOI: 10.1038/nrm3641
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
URI: https://wrap.warwick.ac.uk/84968/

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