The Library
Barriers to living donor kidney transplantation in the United Kingdom : a national observational study
Tools
Tools
Tools
Wu, Diana, Robb, Matthew L., Watson, Christopher J. E., Forsythe, John L. R., Tomson, Charles R. V., Cairns, John, Roderick, Paul, Johnson, Rachel J., Ravanan, Rommel, Fogarty, Damian, Bradley, Clare, Gibbons, Andrea, Metcalfe, Wendy, Draper, Heather, Bradley, J. Andrew and Oniscu, Gabriel C. (2017) Barriers to living donor kidney transplantation in the United Kingdom : a national observational study. Nephrology Dialysis Transplantation, 32 (5). pp. 890-900. doi:10.1093/ndt/gfx036 ISSN 0931-0509.
|
PDF
WRAP-barriers-living-kidney-transplantation-Draper-2017.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons: Attribution-Noncommercial 4.0. Download (1450Kb) | Preview |
|
![[img]](http://wrap.warwick.ac.uk/style/images/fileicons/application_pdf.png) |
PDF
WRAP-barriers-living-kidney-transplantation-Draper-2017.pdf - Accepted Version Embargoed item. Restricted access to Repository staff only - Requires a PDF viewer. Download (1106Kb) |
Official URL: https://doi.org/10.1093/ndt/gfx036
Abstract
Background: Living donor kidney transplantation provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation. This study investigated disparities in the utilisation of living donor kidney transplantation in the UK. Methods: 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of living donor versus deceased donor kidney transplantation were identified. Results: Of 2055 patients, 807 (39.3%) received living donor kidney transplantation and 1248 (60.7%) received deceased donor kidney transplantation. Multivariable modelling demonstrated a significant reduction in the likelihood of living donor kidney transplantation for older age (odds ratio [OR] 0.11, 95% confidence interval [CI] 0.08-0.17, p<0.0001 for 65- 75 years vs 18-34 years), Asian ethnicity (OR 0.55, 95% CI 0.39-0.77, p=0.0006 vs White), Black ethnicity (OR 0.64, 95% CI 0.42-0.99, p=0.047 vs White), divorced, separated or widowed (OR 0.63, 95% CI 0.46-0.88, p=0.030 vs married), no qualifications (OR 0.55, 95% CI 0.42-0.74, p<0.0001 vs higher education qualifications), no car-ownership (OR 0.51, 95% CI 0.37-0.72, p=0.0001), and no home-ownership (OR 0.65, 95% CI 0.85-0.79, p=0.002). The odds of living donor kidney transplantation varied significantly between countries in the UK. Conclusions: Amongst patients undergoing kidney transplantation in the UK, there are significant age, ethnic, socioeconomic and geographic disparities in the utilisation of living donor kidney transplantation. Further work is needed to explore the potential for targeted interventions to improve equity in living donor transplantation.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RD Surgery | ||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Social Science & Systems in Health (SSSH) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||||
| Library of Congress Subject Headings (LCSH): | Kidneys -- Transplantation -- Great Britain, Organ donors | ||||||
| Journal or Publication Title: | Nephrology Dialysis Transplantation | ||||||
| Publisher: | Oxford University Press | ||||||
| ISSN: | 0931-0509 | ||||||
| Official Date: | 31 March 2017 | ||||||
| Dates: |
|
||||||
| Volume: | 32 | ||||||
| Number: | 5 | ||||||
| Page Range: | pp. 890-900 | ||||||
| DOI: | 10.1093/ndt/gfx036 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||
| Date of first compliant deposit: | 15 February 2017 | ||||||
| Date of first compliant Open Access: | 27 July 2017 | ||||||
| Funder: | National Institute for Health Research (Great Britain). Applied Research Programme (ARP NIHR) | ||||||
| Grant number: | RP-PG-0109-10116 | ||||||
| Related URLs: |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
