Stereoselective reductase-catalysed deoxygenation of sulfoxides in aerobic and anaerobic bacteria
UNSPECIFIED. (2004) Stereoselective reductase-catalysed deoxygenation of sulfoxides in aerobic and anaerobic bacteria. ORGANIC & BIOMOLECULAR CHEMISTRY, 2 (4). pp. 554-561. ISSN 1477-0520Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/b313714g
Direct and indirect evidence, Of unexpected stereoselective reductase-catalysed deoxygenations of sulfoxides, was found. The deoxygenations proceeded simultaneously, with the expected dioxygenase-catalysed asymmetric sulfoxidation of sulfides, during some biotransformations with the aerobic bacterium Pseudomonas putida UV4. Stereoselective reductase-catalysed asymmetric deoxygenation of racemic alkylaryl, dialkyl and phenolic sulfoxides was observed, without evidence of the reverse sulfoxidation reaction, using anaerobic bacterial strains. A purified dimethyl sulfoxide reductase, obtained from the intact cells of the anaerobic bacterium Citrobacter braakii DMSO 11, yielded, from the corresponding racemates, enantiopure alkylaryl sulfoxide and thiosulfinate samples.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||ORGANIC & BIOMOLECULAR CHEMISTRY|
|Publisher:||ROYAL SOC CHEMISTRY|
|Date:||21 February 2004|
|Number of Pages:||8|
|Page Range:||pp. 554-561|
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