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A microstereolithography resin based on thiol-ene chemistry : towards biocompatible 3D extracellular constructs for tissue engineering
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Barker, Ian A., Ablett, Matthew P., Gilbert, Hamish T. J., Leigh, Simon J., Covington, James A., Hoyland, Judith A., Richardson, Stephen M. and Dove, Andrew P. (2014) A microstereolithography resin based on thiol-ene chemistry : towards biocompatible 3D extracellular constructs for tissue engineering. Biomaterials Science, 2 (4). pp. 472-475. doi:10.1039/C3BM60290G
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WRAP_C3BM60290G.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1861Kb) | Preview |
Official URL: http://dx.doi.org/10.1039/C3BM60290G
Abstract
A new class of degradable aliphatic poly(carbonate) resins for use in microstereolithographic process is described. Using a biologically inert photo-inhibiting dye, exemplar 3-dimensional structures were produced using thiol–ene chemistry via microstereolithography. Fabricated constructs demonstrated good biological compatibility with cells and had tensile properties that render them suitable for use as tissue engineering scaffolds.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > R Medicine (General) | ||||||||
| Divisions: | Faculty of Science > Chemistry Faculty of Science > Engineering |
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| Library of Congress Subject Headings (LCSH): | Tissue engineering, Osteoarthritis , Intervertebral disk -- Diseases | ||||||||
| Journal or Publication Title: | Biomaterials Science | ||||||||
| Publisher: | R S C Publications | ||||||||
| ISSN: | 2047-4830 | ||||||||
| Official Date: | 18 December 2014 | ||||||||
| Dates: |
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| Volume: | 2 | ||||||||
| Number: | 4 | ||||||||
| Page Range: | pp. 472-475 | ||||||||
| DOI: | 10.1039/C3BM60290G | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access | ||||||||
| Funder: | Research Councils UK (RCUK), Engineering and Physical Sciences Research Council (EPSRC), Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC), Royal Society (Great Britain) | ||||||||
| Grant number: | EP/I014454/1 (EPSRC), BB/I002847/1 (BBSRC) |
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