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A microstereolithography resin based on thiol-ene chemistry : towards biocompatible 3D extracellular constructs for tissue engineering

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Barker, Ian A., Ablett, Matthew P., Gilbert, Hamish T. J., Leigh, Simon J., Covington, James A., Hoyland, Judith A., Richardson, Stephen M. and Dove, Andrew P. (2014) A microstereolithography resin based on thiol-ene chemistry : towards biocompatible 3D extracellular constructs for tissue engineering. Biomaterials Science, 2 (4). pp. 472-475. doi:10.1039/C3BM60290G

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Official URL: http://dx.doi.org/10.1039/C3BM60290G

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Abstract

A new class of degradable aliphatic poly(carbonate) resins for use in microstereolithographic process is described. Using a biologically inert photo-inhibiting dye, exemplar 3-dimensional structures were produced using thiol–ene chemistry via microstereolithography. Fabricated constructs demonstrated good biological compatibility with cells and had tensile properties that render them suitable for use as tissue engineering scaffolds.

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Science, Engineering and Medicine > Science > Chemistry
Faculty of Science, Engineering and Medicine > Engineering > Engineering
Library of Congress Subject Headings (LCSH): Tissue engineering, Osteoarthritis , Intervertebral disk -- Diseases
Journal or Publication Title: Biomaterials Science
Publisher: R S C Publications
ISSN: 2047-4830
Official Date: 18 December 2014
Dates:
DateEvent
18 December 2014Available
9 December 2013Accepted
13 November 2013Submitted
Volume: 2
Number: 4
Page Range: pp. 472-475
DOI: 10.1039/C3BM60290G
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
Funder: Research Councils UK (RCUK), Engineering and Physical Sciences Research Council (EPSRC), Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC), Royal Society (Great Britain)
Grant number: EP/I014454/1 (EPSRC), BB/I002847/1 (BBSRC)

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