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Fractures in kidney transplant recipients : a comparative study between England and New York State
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Arnold, Julia, Mytton, Jemma, Evison, Felicity, Gill, Paramjit, Cockwell, Paul, Sharif, Adnan and Ferro, Charles J. (2017) Fractures in kidney transplant recipients : a comparative study between England and New York State. Experimental and Clinical Transplantation . doi:10.6002/ect.2017.0016 ISSN 1304-0855 .
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WRAP-fractures-kidney-transplant-recipients-Gill-2017.pdf - Accepted Version - Requires a PDF viewer. Download (688Kb) | Preview |
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Official URL: http://doi.org/10.6002/ect.2017.0016
Abstract
Objectives:
Fractures are associated with high morbidity and are a major concern to kidney transplant recipients. There has not been any comparative analysis conducted between countries in the contemporary era to inform future international prevention trials.
Materials and Methods:
Data were obtained from the Hospital Episode Statistics and the Statewide Planning and Research Cooperative databases on all adult kidney transplants performed in England and New York State respectively (2003-2013) and on post-transplant fracture-related hospitalization (2003-2014).
Results:
In total, 18,493 English and 11,602 New York State kidney transplant recipients were included. Overall, 637 (3.4%) English and 398 (3.4%) New York State recipients sustained a fracture giving an unadjusted event rate of 7.0 and 5.9 per 1000 years respectively (P=0.948). A total of 147 (0.8%) English and 101 (0.9%) New York State recipients sustained a hip fracture, giving an unadjusted event rate of 1.6 and 1.5 per 1000 years respectively (P=0.480). There were no differences in the cumulative incidence of all fractures or hip fractures. One-year mortality after any fracture (9% and 11%) or after a hip fracture (15% and 17%) was not different between cohorts.
Conclusions:
Contemporaneous English and New York State kidney transplant recipients have very similar fracture rates and mortality post-fracture.
| Item Type: | Journal Article | ||||||
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| Subjects: | R Medicine > RD Surgery | ||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Social Science & Systems in Health (SSSH) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Kidneys -- Transplantation -- Patients -- Statistics -- New York State, Kidneys -- Transplantation -- Patients -- Statistics -- England, Fractures, Bones -- Diseases, Postoperative period | ||||||
| Journal or Publication Title: | Experimental and Clinical Transplantation | ||||||
| Publisher: | Middle East Society for Organ Transplantation | ||||||
| ISSN: | 1304-0855 | ||||||
| Official Date: | 15 November 2017 | ||||||
| Dates: |
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| DOI: | 10.6002/ect.2017.0016 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||
| Date of first compliant deposit: | 11 April 2017 | ||||||
| Date of first compliant Open Access: | 30 April 2018 | ||||||
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