The Library
Sex-specific lifespan and its evolution in nematodes
Tools
Tools
Tools
Ancell, Henry and Pires-da Silva, André Francisco (2017) Sex-specific lifespan and its evolution in nematodes. Seminars in Cell & Developmental Biology, 70 . pp. 122-129. doi:10.1016/j.semcdb.2017.05.012
|
PDF
WRAP-sex-specific-lifespan-evolution-nematodes-Pires-da Silva-2017.pdf - Accepted Version - Requires a PDF viewer. Download (684Kb) | Preview |
Official URL: http://dx.doi.org/10.1016/j.semcdb.2017.05.012
Abstract
Differences between sexes of the same species in lifespan and aging rate are widespread. While the proximal and evolutionary causes of aging are well researched, the factors that contribute to sex differences in these traits have been less studied. The striking diversity of nematodes provides ample opportunity to study variation in sex-specific lifespan patterns associated with shifts in life history and mating strategy. Although the plasticity of these sex differences will make it challenging to generalize from invertebrate to vertebrate systems, studies in nematodes have enabled empirical evaluation of predictions regarding the evolution of lifespan. These studies have highlighted how natural and sexual selection can generate divergent patterns of lifespan if the sexes are subject to different rates or sources of mortality, or if trade-offs between complex traits and longevity are resolved differently in each sex. Here, we integrate evidence derived mainly from nematodes that addresses the molecular and evolutionary basis of sex-specific aging and lifespan. Ultimately, we hope to generate a clearer picture of current knowledge in this area, and also highlight the limitations of our understanding.
| Item Type: | Journal Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects: | Q Science > QL Zoology | ||||||||
| Divisions: | Faculty of Science > Life Sciences (2010- ) | ||||||||
| Library of Congress Subject Headings (LCSH): | Nematodes -- Aging -- Research, Nematodes -- Aging -- Sex factors, Aging -- Sex factors -- Research | ||||||||
| Journal or Publication Title: | Seminars in Cell & Developmental Biology | ||||||||
| Publisher: | Elsevier Ltd | ||||||||
| ISSN: | 1084-9521 | ||||||||
| Official Date: | October 2017 | ||||||||
| Dates: |
|
||||||||
| Date of first compliant deposit: | 31 May 2017 | ||||||||
| Volume: | 70 | ||||||||
| Page Range: | pp. 122-129 | ||||||||
| DOI: | 10.1016/j.semcdb.2017.05.012 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access | ||||||||
| Funder: | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | ||||||||
| Grant number: | 1499590 (BBSRC) ; BB/L019884/1 (BBSRC) |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
