A new class of Rh(III) catalyst containing an aminoalcohol tethered to a tetramethylcyclopentadienyl hydrogenation group for asymmetric transfer of ketones
UNSPECIFIED. (2004) A new class of Rh(III) catalyst containing an aminoalcohol tethered to a tetramethylcyclopentadienyl hydrogenation group for asymmetric transfer of ketones. TETRAHEDRON LETTERS, 45 (4). pp. 843-846. ISSN 0040-4039Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.tetlet.2003.11.024
The synthesis and application to asymmetric reduction of acetophenone, of a novel class of Rh(III) catalyst containing a tether between the cyclopentadienyl group and a homochiral aminoalcohol, is described. The complex is a highly active catalyst for asymmetric ketone reduction, however it appears to be unstable to the extended reaction conditions. The well-defined stereochemical structure of the catalyst offers potential for significant improvement and 'fine tuning' towards specific substrates. (C) 2003 Elsevier Ltd. All rights reserved.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||TETRAHEDRON LETTERS|
|Publisher:||PERGAMON-ELSEVIER SCIENCE LTD|
|Official Date:||19 January 2004|
|Number of Pages:||4|
|Page Range:||pp. 843-846|
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