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First-episode psychosis and abnormal glycaemic control : authors' reply.
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Perry, Benjamin Ian and Singh, Swaran P. (2017) First-episode psychosis and abnormal glycaemic control : authors' reply. The Lancet Psychiatry, 4 (1). p. 24. doi:10.1016/S2215-0366(16)30411-4
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Official URL: http://dx.doi.org/10.1016/S2215-0366(16)30411-4
Abstract
We thank Karin Fehsel and Stefan Löffler for their thought-provoking summary of the possible role of protein kinase B (Akt) in predisposing people with first-episode psychosis to dysglycaemia, which they consider a potential explanation for the findings of our meta-analysis.1 We found that markers of prediabetes were more common in patients with first-episode psychosis than in healthy matched controls. As they rightly state, we were unable to show causality in our findings, which were observational. However, we did present our own possible explanation; that the two disorders might share intrinsic inflammatory disease links.
| Item Type: | Journal Item | ||||||
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| Subjects: | R Medicine > RC Internal medicine | ||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Psychoses -- Physiological aspects, Schizophrenia -- Physiological aspects, Non-insulin-dependent diabetes -- Physiological aspects, Glycogen synthase kinase-3 | ||||||
| Journal or Publication Title: | The Lancet Psychiatry | ||||||
| Publisher: | Elsevier Ltd. | ||||||
| ISSN: | 2215-0366 | ||||||
| Official Date: | January 2017 | ||||||
| Dates: |
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| Volume: | 4 | ||||||
| Number: | 1 | ||||||
| Page Range: | p. 24 | ||||||
| DOI: | 10.1016/S2215-0366(16)30411-4 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||
| Date of first compliant deposit: | 15 June 2017 | ||||||
| Date of first compliant Open Access: | 1 September 2017 |
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