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Obstructive sleep apnoea and polycystic ovary syndrome ; a comprehensive review of clinical interactions and underlying pathophysiology
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Kahal, Hassan, Kyrou, Ioannis, Tahrani, Abd A. (Almagid) and Randeva, Harpal S. (2017) Obstructive sleep apnoea and polycystic ovary syndrome ; a comprehensive review of clinical interactions and underlying pathophysiology. Clinical Endocrinology, 87 (4). pp. 313-319. doi:10.1111/cen.13392
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Official URL: http://doi.org/10.1111/cen.13392
Abstract
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age. PCOS is associated with multiple co-morbidities including, obesity, insulin resistance and type 2 diabetes, as well as mood disorders and impaired quality of life (QoL). Obstructive sleep apnoea (OSA) is also a common medical condition that is often undiagnosed, particularly in women. OSA is associated with a similar spectrum of comorbidities to that observed in PCOS, including manifestations of the metabolic syndrome and impaired QoL, whilst obesity frequently constitutes a common denominator in the pathophysiology of both OSA and PCOS. Hence, it is not surprising that OSA and PCOS may co-exist in women of reproductive age, and the current clinical guidelines on the management of PCOS recommend screening for OSA symptoms in overweight/obese women with PCOS. In this review, we examine the relationship between OSA and PCOS and explore the potential underlying mechanisms that link these two conditions. This article is protected by copyright. All rights reserved. [Abstract copyright: This article is protected by copyright. All rights reserved.]
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RC Internal medicine R Medicine > RG Gynecology and obstetrics |
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| Divisions: | Faculty of Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine Faculty of Medicine > Warwick Medical School |
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| SWORD Depositor: | Library Publications Router | ||||||||
| Library of Congress Subject Headings (LCSH): | Sleep apnea syndromes, Polycystic ovary syndrome | ||||||||
| Journal or Publication Title: | Clinical Endocrinology | ||||||||
| Publisher: | Wiley-Blackwell Publishing Ltd | ||||||||
| ISSN: | 0300-0664 | ||||||||
| Official Date: | October 2017 | ||||||||
| Dates: |
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| Date of first compliant deposit: | 6 July 2017 | ||||||||
| Volume: | 87 | ||||||||
| Number: | 4 | ||||||||
| Page Range: | pp. 313-319 | ||||||||
| DOI: | 10.1111/cen.13392 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Publisher Statement: | ** From PubMed via Jisc Publications Router. | ||||||||
| Access rights to Published version: | Restricted or Subscription Access |
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