Jaekel, Julia, Baumann, Nicole, Bartmann, Peter and Wolke, Dieter (2018) Mood and anxiety disorders in very preterm/very low-birth weight individuals from 6 to 26 years. Journal of Child Psychology and Psychiatry, 59 (1). pp. 88-95. doi:10.1111/jcpp.12787

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Abstract

Background

Very preterm (<32 weeks’ gestational age; VP) or very low–birth weight (<1,500 g; VLBW) birth has been associated with increased risk for anxiety and mood disorders and less partnering in adulthood. The aim was to test whether (a) VP/VLBW are at increased risk of any anxiety or mood disorders from 6 to 26 years compared with term-born individuals; (b) social support from romantic partners is associated with protection from anxiety and mood disorders; and (c) VP/VLBW adults’ lower social support mediates their risk for any anxiety and mood disorders.
Methods

Data are from a prospective geographically defined longitudinal whole-population study in South Bavaria (Germany). Two hundred VP/VLBW and 197 term individuals were studied from birth to adulthood. Anxiety and mood disorders were assessed at 6, 8, and 26 years with standardized diagnostic interviews and social support via self-report at age 26.
Results

At age 6, VP/VLBW children were not at increased risk of any anxiety or mood disorder. At age 8, VP/VLBW more often had any anxiety disorder than term comparisons (11.8% vs. 6.6%, OR = 2.10, 95% CI [1.08–4.10]). VP/VLBW adults had an increased risk for any mood (27.5% vs. 18.8%, OR = 1.65 [1.02–2.67]) but not for any anxiety disorder (33.0% vs. 28.4%, OR = 1.27 [0.82–1.96]). None of the significant differences survived correction for multiple testing. Social support was associated with a lower risk of anxiety or mood disorders in both groups (OR = 0.81 [0.68–0.96]) and mediated the association of VP/VLBW birth with any anxiety or any mood disorders at age 26.
Conclusions

This study does not show a persistently increased risk for any anxiety or mood disorder after VP/VLBW birth. Low social support from a romantic partner mediates the risk for anxiety or mood disorders after VP/VLBW birth.

Item Type:	Journal Article
Subjects:	B Philosophy. Psychology. Religion > BF Psychology H Social Sciences > HQ The family. Marriage. Woman R Medicine > RC Internal medicine R Medicine > RJ Pediatrics
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science > Psychology Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Affective disorders, Mood (Psychology), Prematurely born children, Premature infants, Birth weight, Low
Journal or Publication Title:	Journal of Child Psychology and Psychiatry
Publisher:	Wiley-Blackwell Publishing Ltd.
ISSN:	0021-9630
Official Date:	January 2018
Dates:	Date Event January 2018 Published 27 July 2017 Available 7 June 2017 Accepted
Volume:	59
Number:	1
Page Range:	pp. 88-95
DOI:	10.1111/jcpp.12787
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Germany. Bundesministerium für Bildung und Wissenschaft
Grant number:	PKE24, JUG14, 01EP9504 and 01ER0801

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