UNSPECIFIED. (2003) Multilocus sequence typing for comparison of veterinary and human isolates of Campylobacter jejuni. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 69 (11). pp. 6370-6379. ISSN 0099-2240

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Abstract

Multilocus sequence typing (MLST) has been applied to 266 Campylobacter jejuni isolates, mainly from veterinary sources, including cattle, sheep, poultry, pigs, pets, and the environment, as well as isolates from human cases of campylobacteriosis. The populations of veterinary and human isolates overlap, suggesting that most veterinary sources should be considered reservoirs of pathogenic campylobacters. There were some associations between source and sequence type complex, indicating that host or source adaptation may exist. The pig isolates formed a distinct group by MLST and may well represent a potential pig-adapted clone of C jejuni. A subset (n = 82) of isolates was reanalyzed with a second MLST scheme which provided a unique set of isolates that had been analyzed at a total of 12 loci. The distribution of isolates among the complexes in each of the two schemes was similar but not identical. In addition to isolates from human outbreaks, one group of isolates that were not epidemiologically linked was also identical at all 12 loci. This group of isolates is believed to represent another stable strain of C. jejuni.

Item Type:	Journal Article
Subjects:	T Technology > TP Chemical technology Q Science > QR Microbiology
Journal or Publication Title:	APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Publisher:	AMER SOC MICROBIOLOGY
ISSN:	0099-2240
Date:	November 2003
Volume:	69
Number:	11
Number of Pages:	10
Page Range:	pp. 6370-6379
Identification Number:	10.1128/AEM.69.11.6370-6379.2003
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/9165

Data sourced from Thomson Reuters' Web of Knowledge

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