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A one-pot process for the enantioselective synthesis of amines via reductive amination under transfer hydrogenation conditions
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UNSPECIFIED. (2003) A one-pot process for the enantioselective synthesis of amines via reductive amination under transfer hydrogenation conditions. ORGANIC LETTERS, 5 (22). pp. 4227-4230. ISSN 1523-7060
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Official URL: http://dx.doi.org/10.1021/ol035746r
Abstract
Cyclic amines may be prepared via a sequence of deprotection followed by intramolecular reductive amination of t-Boc-protected amino ketones under asymmetric transfer hydrogenation conditions. In cases where the corresponding imine reaction proceeds with high enantioselectivity, this is reflected in the one-step process.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Journal or Publication Title: | ORGANIC LETTERS |
| Publisher: | AMER CHEMICAL SOC |
| ISSN: | 1523-7060 |
| Date: | 30 October 2003 |
| Volume: | 5 |
| Number: | 22 |
| Number of Pages: | 4 |
| Page Range: | pp. 4227-4230 |
| Identification Number: | 10.1021/ol035746r |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/9188 |
Data sourced from Thomson Reuters' Web of Knowledge
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