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Regulation of [Ca2+](c) oscillations by plasma membrane Ca2+ fluxes: a role for natriuretic peptides
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UNSPECIFIED (2003) Regulation of [Ca2+](c) oscillations by plasma membrane Ca2+ fluxes: a role for natriuretic peptides. In: 5th UK Calcium Signalling Conference, UNIV LIVERPOOL, LIVERPOOL, ENGLAND, MAY 01-02, 2003. Published in: BIOCHEMICAL SOCIETY TRANSACTIONS, 31 (Part 5). pp. 934-938. ISSN 0300-5127.
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Abstract
We have investigated the effects of natriuretic peptides on oscillations in [Ca2+](c) (cytosolic free Ca2+ concentration) in two different cell types: freshly isolated rat hepatocytes and the ECV304 cell line. Our data, from both cell types, suggest that natriuretic peptides modulate the frequency of [Ca2+](c) oscillations through alterations in plasma membrane Ca2+ fluxes. Here, we review evidence for a role for plasma membrane Ca2+ fluxes in the control of the frequency of [Ca2+](c) oscillations. We describe a hypothetical mechanism through which this might be achieved. We propose a physiological role for regulated control of Ca2+ efflux in modulating [Ca2+](c) oscillations.
Item Type: | Conference Item (UNSPECIFIED) | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | BIOCHEMICAL SOCIETY TRANSACTIONS | ||||
Publisher: | PORTLAND PRESS | ||||
ISSN: | 0300-5127 | ||||
Official Date: | October 2003 | ||||
Dates: |
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Volume: | 31 | ||||
Number: | Part 5 | ||||
Number of Pages: | 5 | ||||
Page Range: | pp. 934-938 | ||||
Publication Status: | Published | ||||
Title of Event: | 5th UK Calcium Signalling Conference | ||||
Location of Event: | UNIV LIVERPOOL, LIVERPOOL, ENGLAND | ||||
Date(s) of Event: | MAY 01-02, 2003 |
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