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Base-mediated reactions of N-alkyl-O-acyl hydroxamic acids: synthesis of 3-oxo-2,3-dihydro-4-isoxazole carboxylic ester derivatives
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UNSPECIFIED. (2003) Base-mediated reactions of N-alkyl-O-acyl hydroxamic acids: synthesis of 3-oxo-2,3-dihydro-4-isoxazole carboxylic ester derivatives. TETRAHEDRON LETTERS, 44 (42). pp. 7763-7765. ISSN 0040-4039
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Official URL: http://dx.doi.org/10.1016/j.tetlet.2003.08.098
Abstract
Treatment of malonyl derived O-acyl hydroxamic acid derivatives 10a-h with the phosphazene super base P-2-t-Bu 7 gives 2,3-dihydro-4-isoxazole carboxylic ester derivatives 11a-h. The rate and yield of the reaction is dependent upon the O-acyl substituent. (C) 2003 Published by Elsevier Ltd.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Journal or Publication Title: | TETRAHEDRON LETTERS |
| Publisher: | PERGAMON-ELSEVIER SCIENCE LTD |
| ISSN: | 0040-4039 |
| Date: | 13 October 2003 |
| Volume: | 44 |
| Number: | 42 |
| Number of Pages: | 3 |
| Page Range: | pp. 7763-7765 |
| Identification Number: | 10.1016/j.tetlet.2003.08.098 |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/9239 |
Data sourced from Thomson Reuters' Web of Knowledge
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