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Base-mediated reactions of N-alkyl-O-acyl hydroxamic acids: synthesis of 3-oxo-2,3-dihydro-4-isoxazole carboxylic ester derivatives
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UNSPECIFIED (2003) Base-mediated reactions of N-alkyl-O-acyl hydroxamic acids: synthesis of 3-oxo-2,3-dihydro-4-isoxazole carboxylic ester derivatives. TETRAHEDRON LETTERS, 44 (42). pp. 7763-7765. doi:10.1016/j.tetlet.2003.08.098 ISSN 0040-4039.
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Official URL: http://dx.doi.org/10.1016/j.tetlet.2003.08.098
Abstract
Treatment of malonyl derived O-acyl hydroxamic acid derivatives 10a-h with the phosphazene super base P-2-t-Bu 7 gives 2,3-dihydro-4-isoxazole carboxylic ester derivatives 11a-h. The rate and yield of the reaction is dependent upon the O-acyl substituent. (C) 2003 Published by Elsevier Ltd.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | TETRAHEDRON LETTERS | ||||
Publisher: | PERGAMON-ELSEVIER SCIENCE LTD | ||||
ISSN: | 0040-4039 | ||||
Official Date: | 13 October 2003 | ||||
Dates: |
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Volume: | 44 | ||||
Number: | 42 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 7763-7765 | ||||
DOI: | 10.1016/j.tetlet.2003.08.098 | ||||
Publication Status: | Published |
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