The Library
Bio-inks for 3D bioprinting : recent advances and future prospects
Tools
Donderwinkel, Ilze, van Hest, Jan C. M. and Cameron, Neil R. (2017) Bio-inks for 3D bioprinting : recent advances and future prospects. Polymer Chemistry, 8 (31). pp. 4451-4471. doi:10.1039/C7PY00826K ISSN 1759-9954.
|
PDF
WRAP-Bio-inks-3D-printing-Cameron-2017.pdf - Accepted Version - Requires a PDF viewer. Download (1874Kb) | Preview |
Official URL: http://dx.doi.org/10.1039/C7PY00826K
Abstract
In the last decade, interest in the field of three-dimensional (3D) bioprinting has increased enormously. 3D bioprinting combines the fields of developmental biology, stem cells, and computer and materials science to create complex bio-hybrid structures for various applications. It is able to precisely place different cell types, biomaterials and biomolecules together in a predefined position to generate printed composite architectures. In the field of tissue engineering, 3D bioprinting has allowed the study of tissues and organs on a new level. In clinical applications, new models have been generated to study disease pathogenesis. One of the most important components of 3D bio-printing is the bio-ink, which is a mixture of cells, biomaterials and bioactive molecules that creates the printed article. This review describes all the currently used bio-printing inks, including polymeric hydrogels, polymer bead microcarriers, cell aggregates and extracellular matrix proteins. Amongst the polymeric components in bio-inks are: natural polymers including gelatin, hyaluronic acid, silk proteins and elastin; and synthetic polymers including amphiphilic block copolymers, PEG, poly(PNIPAAM) and polyphosphazenes. Furthermore, photocrosslinkable and thermoresponsive materials are described. To provide readers with an understanding of the context, the review also contains an overview of current bio-printing techniques and finishes with a summary of bio-printing applications.
Item Type: | Journal Article | ||||||
---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||||
Journal or Publication Title: | Polymer Chemistry | ||||||
Publisher: | Royal Society of Chemistry | ||||||
ISSN: | 1759-9954 | ||||||
Official Date: | 10 July 2017 | ||||||
Dates: |
|
||||||
Volume: | 8 | ||||||
Number: | 31 | ||||||
Page Range: | pp. 4451-4471 | ||||||
DOI: | 10.1039/C7PY00826K | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||
Date of first compliant deposit: | 31 October 2017 | ||||||
Date of first compliant Open Access: | 10 July 2018 |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year