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Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids
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Thind, R., O'Neill, D. W., Del Regno, Annalaura and Notman, Rebecca (2015) Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids. Chemical Communications, 51 (25). pp. 5406-5409. doi:10.1039/c4cc08527b
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Abstract
We show that ethanol can induce the formation of water-permeable defects in model membranes of skin, providing a fresh perspective on ethanol as a membrane modulator. We rationalise our findings in terms of the chemical nature of ethanol, i.e., a combination of its hydrogen bonding propensity and amphiphilic character.
| Item Type: | Journal Article | |||||||||
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| Subjects: | Q Science > QP Physiology | |||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | |||||||||
| SWORD Depositor: | Library Publications Router | |||||||||
| Library of Congress Subject Headings (LCSH): | Skin -- Physiology, Lipids, Ethanol | |||||||||
| Journal or Publication Title: | Chemical Communications | |||||||||
| Publisher: | Royal Society of Chemistry (RSC) | |||||||||
| ISSN: | 1364-548X | |||||||||
| Official Date: | 2015 | |||||||||
| Dates: |
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| Volume: | 51 | |||||||||
| Number: | 25 | |||||||||
| Page Range: | pp. 5406-5409 | |||||||||
| DOI: | 10.1039/c4cc08527b | |||||||||
| Status: | Peer Reviewed | |||||||||
| Publication Status: | Published | |||||||||
| Reuse Statement (publisher, data, author rights): | ** From Crossref via Jisc Publications Router. | |||||||||
| RIOXX Funder/Project Grant: |
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