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Stable-isotope probing of nucleic acids: a window to the function of uncultured microorganisms
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UNSPECIFIED (2003) Stable-isotope probing of nucleic acids: a window to the function of uncultured microorganisms. [Journal Item]
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Official URL: http://dx.doi.org/10.1016/S0958-1669(03)00064-8
Abstract
Phylogeny based on ribosomal RNA sequences alone is rarely a reliable indicator of microbial function. To circumvent this problem, nucleic acid based techniques have been developed that exploit the physical properties of stable isotopes to study microbially mediated processes within complex environmental samples. Investigations using labelled substrates, or which detect variations in the natural abundance of isotopes, have thus revealed the metabolic function of microorganisms without the need to isolate them in culture.
| Item Type: | Journal Item |
|---|---|
| Subjects: | Q Science > QD Chemistry T Technology > TP Chemical technology |
| Journal or Publication Title: | CURRENT OPINION IN BIOTECHNOLOGY |
| Publisher: | CURRENT BIOLOGY LTD |
| ISSN: | 0958-1669 |
| Date: | June 2003 |
| Volume: | 14 |
| Number: | 3 |
| Number of Pages: | 7 |
| Page Range: | pp. 296-302 |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/9537 |
Data sourced from Thomson Reuters' Web of Knowledge
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