Rosacea: A cutaneous marker of Helicobacter pylori infection? Results of a pilot study
UNSPECIFIED. (2003) Rosacea: A cutaneous marker of Helicobacter pylori infection? Results of a pilot study. ACTA DERMATO-VENEREOLOGICA, 83 (4). pp. 282-286. ISSN 0001-5555Full text not available from this repository.
Given the long purported anecdotal association between rosacea and gastrointestinal disease, the discovery that Helicobacter pylori causes gastritis and duodenal ulcer disease has led to a hypothesized role for this organism in the aetiology of rosacea. We conducted a case-series study of 49 patients to assess the potential association between severity of rosacea and direct and serological evidence of H. pylori infection. Patients were classified by severity into non-inflammatory erythematotelangiectatic or inflammatory/papulopustular rosacea and were tested for current H. pylori infection and evidence of previous exposure. Positive C-13-urea breath test and ELISA tests were more likely to be observed in patients with inflammatory rosacea, although not statistically significantly so (OR = 3.0, p = 0.15 and OR = 2.9, p = 0.16, respectively). However, the proportion of patients who tested positive in both assays (versus negative in at least one) was even higher in the inflammatory rosacea group and neared statistical significance (OR = 4.5, p = 0.06). This pilot study provides sufficient evidence suggestive of a positive association between the severity of rosacea and the presence of H. pylori to warrant further research.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RL Dermatology|
|Journal or Publication Title:||ACTA DERMATO-VENEREOLOGICA|
|Publisher:||TAYLOR & FRANCIS AS|
|Number of Pages:||5|
|Page Range:||pp. 282-286|
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