Nuclear immunostaining in rat neuronal cells using two anti-Kir2.2 ion channel polyclonal antibodies
UNSPECIFIED. (2003) Nuclear immunostaining in rat neuronal cells using two anti-Kir2.2 ion channel polyclonal antibodies. JOURNAL OF MOLECULAR NEUROSCIENCE, 20 (2). pp. 189-193. ISSN 0895-8696Full text not available from this repository.
The inwardly rectifying potassium ion channel Kir2.2 has recently been demonstrated to have nuclear and plasma membrane subcellular localization. Nuclear expression of Kir2.2 is controversial, as a functional role for Kir2.0 potassium channels in the nucleus has not been investigated. However, in this report we have demonstrated Kir2.2 nuclear localization in sections of rat hindbrain and dorsal root ganglia tissue, using two anti-Kir2.2 polyclonal antisera with different epitope specificities. These data confirm nuclear localization and are suggestive of new functions of Kir2.0 potassium ion channels in the nucleus.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
|Journal or Publication Title:||JOURNAL OF MOLECULAR NEUROSCIENCE|
|Publisher:||HUMANA PRESS INC|
|Official Date:||April 2003|
|Number of Pages:||5|
|Page Range:||pp. 189-193|
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